CAJ | 학술논문

目的：探讨血浆脑钠肽前体（Pro－brain natriuretic peptide，Pro－BNP）检测对心源性脑栓塞（Cardioembolic，CE）诊断价值。方法：连续登记2013年10月～2014年1月我院神经内科收住的92例急性脑梗死（Cerebral infarction，CI）患者，检测患者血浆Pro－BNP水平，根据TOAST诊断标准分为CE组（n＝38）和非CE组（n＝54），比较两组血浆Pro－BNP水平差异性。结果：CI组患者血浆Pro－BNP水平明显高于正常对照组（中位数413．1 vs 68．06，P＜0．01）；CE组血浆Pro－BNP水平明显高于非CE组（中位数1618 vs 121．9，P＜0．01）。结论：血浆Pro－BNP水平检测有助于脑梗死病因学分型，有利于早期开展脑梗死二级预防治疗。
목적：탐토혈장뇌납태전체（Pro－brain natriuretic peptide，Pro－BNP）검측대심원성뇌전새（Cardioembolic，CE）진단개치。방법：련속등기2013년10월～2014년1월아원신경내과수주적92례급성뇌경사（Cerebral infarction，CI）환자，검측환자혈장Pro－BNP수평，근거TOAST진단표준분위CE조（n＝38）화비CE조（n＝54），비교량조혈장Pro－BNP수평차이성。결과：CI조환자혈장Pro－BNP수평명현고우정상대조조（중위수413．1 vs 68．06，P＜0．01）；CE조혈장Pro－BNP수평명현고우비CE조（중위수1618 vs 121．9，P＜0．01）。결론：혈장Pro－BNP수평검측유조우뇌경사병인학분형，유리우조기개전뇌경사이급예방치료。
Objective:To assess the diagnostic value of plasma pro-brain natriuretic peptide( Pro-BNP) in cardioembolic ischemic stroke .Methods:Con-secutive 92 patients with cerebral infarction(CI) admitted to our department were included from October 2013 through January 2014,and allocated to car-dioembolic(CE) group(n=38) and non-cardioembolic(non-CE) group(n=54) according to TOAST criteria.The two groups of patients were undergone comparison of the Pro-BNP levels measured.Results:The Pro-BNP level in CI group was significant higher than that of normal control group(median 413.1 vs.68.06,P<0.01),and higher Pro-BNP levels were also observed in CE group as compared with non-CE group(median 1 618 vs.121.9,P<0.01). Conclusion:Measurement of Pro-BNP level may contribute to clarifying the etiologic subtypes of cerebral infarction and its early prevention and treatment .