CAJ | 학술논문

目的：探讨经皮冠状动脉介入(PCI)和静脉溶栓在急性心肌梗死患者中的应用价值。方法选择我院2013年1月至2014年9月收治的60例急性心肌梗死患者作为研究对象，随机分为实验组和对照组各30例。实验组患者采用PCI治疗，对照组患者采用静脉溶栓治疗，比较两组患者血管再通率、死亡发生率、ST段回落情况、住院时间、近远期不良事件发生率、左室舒张末径和左室射血分数变化情况。结果实验组血管再通率显著高于对照组，差异有统计学意义(P<0.05)，而近期和远期不良事件发生率均低于对照组，近期不良事件发生率组间比较差异有统计学意义(P<0.05)，而远期不良事件发生率比较差异无统计学意义(P>0.05)。实验组患者死亡发生率、ST段回落和住院时间均低于对照组，差异均有统计学意义(P<0.05)。实验组左室射血分数在术后1个月、3个月和6个月时均显著高于对照组，差异均有统计学意义(P<0.05)。结论急性心肌梗死患者应用PCI治疗可显著提高血管再通率、降低死亡和不良事件发生率，有效改善心功能。
목적：탐토경피관상동맥개입(PCI)화정맥용전재급성심기경사환자중적응용개치。방법선택아원2013년1월지2014년9월수치적60례급성심기경사환자작위연구대상，수궤분위실험조화대조조각30례。실험조환자채용PCI치료，대조조환자채용정맥용전치료，비교량조환자혈관재통솔、사망발생솔、ST단회락정황、주원시간、근원기불량사건발생솔、좌실서장말경화좌실사혈분수변화정황。결과실험조혈관재통솔현저고우대조조，차이유통계학의의(P<0.05)，이근기화원기불량사건발생솔균저우대조조，근기불량사건발생솔조간비교차이유통계학의의(P<0.05)，이원기불량사건발생솔비교차이무통계학의의(P>0.05)。실험조환자사망발생솔、ST단회락화주원시간균저우대조조，차이균유통계학의의(P<0.05)。실험조좌실사혈분수재술후1개월、3개월화6개월시균현저고우대조조，차이균유통계학의의(P<0.05)。결론급성심기경사환자응용PCI치료가현저제고혈관재통솔、강저사망화불량사건발생솔，유효개선심공능。
Objective To evaluate the application value of percutaneous coronary intervention (PCI) and in-travenous thrombolysis in patients with acute myocardial infarction. Methods Sixty patients from February 2013 to September 2014 in our hospital were chosen as the study objects, which were divided into experimental group and con-trol group randomly. The control group was treated with intravenous thrombolysis, and the experimental group was treated with PCI. The recanalization rate, death rate, ST segment resolution, hospitalization time, short-term and long-term adverse event rates, left ventricular enddiastolic dimension and left ventricular ejection fraction change were compared. Results In experimental group, the recanalization rate was significantly higher than that in the control group, and the difference was statistically significant (P<0.05). The short-term and long-term adverse event rates were lower than those in the control group, with statistically significant difference between the two groups for short-term adverse event rates (P<0.05) and no significant difference for long-term adverse event rates (P>0.05). The death rate, ST segment resolution, hospitalization time of experimental group was lower than those of the control group, and the difference was statistically significant (P<0.05). In experimental group, the left ventricular ejection fraction after Janu-ary, March and June were higher than that in the control group (P<0.05). Conclusion Application of PCI in patients with acute myocardial infarction treatment can significantly improve the rate of recanalization, reduce the incidence of death and adverse events, and improve heart function.