CAJ | 학술논문

目的：分析胺碘酮在室性心律失常治疗中的效果。方法选取室性心律失常患者130例，随机均分为实验组和对照组（n=65），对照组予以常规抗心律失常治疗，实验组在对照组基础上加用胺碘酮。比较2组患者临床疗效和不良反应。结果对照组疗效优、良、中、差人数分别为21、32、8、4例，总优良率81.54%；实验组疗效优、良、中、差人数分别为27、35、3、0例，总优良率95.38%；实验组总优良率明显高于对照组，2组差异具有统计学意义（P＜0.05）。实验组不良反应发生率为6.15%，稍高于对照组4.62%，差异无统计学意义。结论胺碘酮治疗室性心律失常疗效显著，且安全性广，不良反应少且轻，值得临床推广。
목적：분석알전동재실성심률실상치료중적효과。방법선취실성심률실상환자130례，수궤균분위실험조화대조조（n=65），대조조여이상규항심률실상치료，실험조재대조조기출상가용알전동。비교2조환자림상료효화불량반응。결과대조조료효우、량、중、차인수분별위21、32、8、4례，총우량솔81.54%；실험조료효우、량、중、차인수분별위27、35、3、0례，총우량솔95.38%；실험조총우량솔명현고우대조조，2조차이구유통계학의의（P＜0.05）。실험조불량반응발생솔위6.15%，초고우대조조4.62%，차이무통계학의의。결론알전동치료실성심률실상료효현저，차안전성엄，불량반응소차경，치득림상추엄。
Objective To analyze the effect of amiodarone in the treatment of ventricular arrhythmias.Methods 130 patients with ventricular arrhythmiasand were selected and randomly divided into the experimental group and the control group(n=65). The control group was treated with routine antiarrhythmic therapy, and the experimental group was treated with amiodarone on the basis of control group. The clinical efficacy and adverse reactions of two groups were compared.Results The number of the excellent, good, fair, poor in control group was 21, 32, 8, 4, and the excellent and good rate was 81.54%; while The number of the excellent, good, fair, poor in experimental group was 27, 35, 3, 0, and the excellent and good rate was 95.38%. The excellent and good rate of experimental group was significantly higher than that of control group, the difference had statistical significance (P<0.05). The incidence of adverse reactions in the experimental group (6.15%) was slightly higher than the control group(4.62%), but the difference wasn’t statistically significant.Conclusion The efficacy of amiodarone in the treatment of ventricular arrhythmias is significant and extensive safe, it’s adverse reactions was light, and it is worthy of promotion.