CAJ | 학술논문

乳腺癌属于全身性疾病，是发生在乳腺腺上皮组织的恶性肿瘤，乳腺癌的发生发展是内分泌、免疫系统等诸多因素共同作用的结果，乳腺癌细胞因子及受体可反映肿瘤的生物学特性，本文就血清细胞因子中的肿瘤坏死因子-α(TNF-α)、转化生长因子-β1(TGF-β1)、趋化因子CCL20以及与它们相关的受体即可溶性受体p55(sTNFR-p55)、可溶性CD105(S-CD105)、趋化因子受体CXCR3在乳腺癌的诊断、疗效监控和判断预后的意义做一综述。
유선암속우전신성질병，시발생재유선선상피조직적악성종류，유선암적발생발전시내분비、면역계통등제다인소공동작용적결과，유선암세포인자급수체가반영종류적생물학특성，본문취혈청세포인자중적종류배사인자-α(TNF-α)、전화생장인자-β1(TGF-β1)、추화인자CCL20이급여타문상관적수체즉가용성수체p55(sTNFR-p55)、가용성CD105(S-CD105)、추화인자수체CXCR3재유선암적진단、료효감공화판단예후적의의주일종술。
Breast cancer is a systemic disease, which is a malignant tumor occurred in the epithelial tissues of mammary gland. The development of breast cancer is a combined action of endocrine, immune system and many other factors. Factor and its receptor in breast cancer cells can reflect the biological characteristics of tumors. This article re-viewed the roles of some serum cytokines, such as the tumor necrosis factor alpha (TNF-α), soluble P55 (sTN-FR-P55), transforming growth factor-β1 (TGF-β1), soluble CD105 (S-CD105), chemotactic factor CCL20 and chemotac-tic factor receptor CXCR3 in diagnosis, curative effect monitoring and prognosis of breast cancer.