CAJ | 학술논문

滑膜间充质干细胞(Synovium-derived mesenchymal stem cells，SMCSs)的增殖能力强，分离方法简便，具有多向分化潜能。其中SMSCs的成软骨分化能力尤为突出，被广泛应用于软骨缺损修复的实验中，因此SMSCs可能成为软骨组织工程领域中新的种子细胞，为关节软骨疾病治疗提供了新的可能性。本文对SMSCs的组织来源、生物学特性以及在软骨组织工程中的应用展开综述。
활막간충질간세포(Synovium-derived mesenchymal stem cells，SMCSs)적증식능력강，분리방법간편，구유다향분화잠능。기중SMSCs적성연골분화능력우위돌출，피엄범응용우연골결손수복적실험중，인차SMSCs가능성위연골조직공정영역중신적충자세포，위관절연골질병치료제공료신적가능성。본문대SMSCs적조직래원、생물학특성이급재연골조직공정중적응용전개종술。
Besides the general multipotency in common with other MSCs, synovium-derived mesenchymal stem cells exhibit easy access to cell resources and higher ability of proliferation and superiority in chondrogenesis. Under appropriate culture conditions, SMSCs were induced to differentiate into chondrocyte, osteocyte, and adipocyte lineages. This provides a new MSC-based therapeutic strategy for the repair of cartilage injury. This article expands overview of the tissue origin, biological characteristics of SMSCs and application in cartilage tissue engineering.