CAJ | 학술논문

目的：探讨血清乳酸及降钙素原(PCT)测定在腹腔感染中的临床意义。方法选取2012年3月至2013年3月在我院普外科病区收治的腹腔感染患者总计65例。所有患者根据疾病转归分成存活组和死亡组，其中死亡组23例，存活组42例。同时选取同期体检者作为正常对照组共计30例。入院时、入院后12 h、24 h、48 h抽取静脉血，检测血清乳酸及降钙素原指标。结果死亡组、存活组在各时间点血清乳酸、降钙素原水平均高于正常对照组，差异有统计学意义(P<0.05)。死亡组在各时间点血清乳酸、降钙素原水平均高于存活组，差异有统计学意义(P<0.05)。结论血清乳酸及降钙素原水平在腹腔感染的严重度和转归预测中具有一定的临床意义。
목적：탐토혈청유산급강개소원(PCT)측정재복강감염중적림상의의。방법선취2012년3월지2013년3월재아원보외과병구수치적복강감염환자총계65례。소유환자근거질병전귀분성존활조화사망조，기중사망조23례，존활조42례。동시선취동기체검자작위정상대조조공계30례。입원시、입원후12 h、24 h、48 h추취정맥혈，검측혈청유산급강개소원지표。결과사망조、존활조재각시간점혈청유산、강개소원수평균고우정상대조조，차이유통계학의의(P<0.05)。사망조재각시간점혈청유산、강개소원수평균고우존활조，차이유통계학의의(P<0.05)。결론혈청유산급강개소원수평재복강감염적엄중도화전귀예측중구유일정적림상의의。
Objective To analyze the clinical significance of serum lactic acid and procalcitonin (PCT) in ab-dominal infection. Methods Sixty-five patients defined as abdominal infection in the Department of General Sur-gery in our hospital from Mar. 2012 to Mar. 2013 were collected. All the patients were divided into survival group and death group according to the prognosis of disease, with 23 cases in the death group and 42 cases in the survival group. Thirty healthy volunteers (control group) were selected from medical examination center. Venous blood was extracted from patients when they were in hospital after 12 h, 24 h, 48 h. The levels of lactic acid and PCT were detected from the venous blood. Results The levels of serum lactic acid and PCT in the death group and survival group were all sig-nificantly higher than the control group at each time points (P<0.05). The levels of death group were significantly high-er than those of survival group in each time point, with statistically significant difference (P<0.05). Conclusion The levels of serum lactic acid and PCT are closely related to the severity of abdominal infection and may be used as index-es for the estimation of prognosis and the effect of treatment.