中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
2期
91-92,95
,共3页
门冬氨酸钾镁针剂%室性期前收缩%临床效果
門鼕氨痠鉀鎂針劑%室性期前收縮%臨床效果
문동안산갑미침제%실성기전수축%림상효과
Potassium-magnesium aspartate injection%Ventricular premature contraction%Clinical efficacy
目的：观察门冬氨酸钾镁针剂治疗室性期前收缩的临床效果。方法将2009年1月~2013年1月入院行动态心电图检查，动态心电图24 h室性期前收缩>4000次，符合入选标准的86例患者，随机分为治疗组(50例)和对照组(36例)，对照组选择美托洛尔、美西律、普罗帕同、胺碘酮等常规抗心律失常治疗，治疗组在对照组治疗的基础上给予门冬氨酸钾镁针剂。治疗前后监测血清钾、镁的变化。结果治疗组治疗前后血清钾、镁差异有统计学意义(P<0.05，P<0.01)，对照组治疗前后血清钾、镁差异无统计学意义(P>0.05)；治疗组与对照组治疗后血清钾差异有统计学意义(P<0.05)，血清镁差异无统计学意义(P>0.05)。治疗组总有效率为78.00%，显著高于对照组的55.56%，差异有统计学意义(P<0.05)。结论门冬氨酸钾镁针剂治疗室性期前收缩疗效显著。
目的：觀察門鼕氨痠鉀鎂針劑治療室性期前收縮的臨床效果。方法將2009年1月~2013年1月入院行動態心電圖檢查，動態心電圖24 h室性期前收縮>4000次，符閤入選標準的86例患者，隨機分為治療組(50例)和對照組(36例)，對照組選擇美託洛爾、美西律、普囉帕同、胺碘酮等常規抗心律失常治療，治療組在對照組治療的基礎上給予門鼕氨痠鉀鎂針劑。治療前後鑑測血清鉀、鎂的變化。結果治療組治療前後血清鉀、鎂差異有統計學意義(P<0.05，P<0.01)，對照組治療前後血清鉀、鎂差異無統計學意義(P>0.05)；治療組與對照組治療後血清鉀差異有統計學意義(P<0.05)，血清鎂差異無統計學意義(P>0.05)。治療組總有效率為78.00%，顯著高于對照組的55.56%，差異有統計學意義(P<0.05)。結論門鼕氨痠鉀鎂針劑治療室性期前收縮療效顯著。
목적：관찰문동안산갑미침제치료실성기전수축적림상효과。방법장2009년1월~2013년1월입원행동태심전도검사，동태심전도24 h실성기전수축>4000차，부합입선표준적86례환자，수궤분위치료조(50례)화대조조(36례)，대조조선택미탁락이、미서률、보라파동、알전동등상규항심률실상치료，치료조재대조조치료적기출상급여문동안산갑미침제。치료전후감측혈청갑、미적변화。결과치료조치료전후혈청갑、미차이유통계학의의(P<0.05，P<0.01)，대조조치료전후혈청갑、미차이무통계학의의(P>0.05)；치료조여대조조치료후혈청갑차이유통계학의의(P<0.05)，혈청미차이무통계학의의(P>0.05)。치료조총유효솔위78.00%，현저고우대조조적55.56%，차이유통계학의의(P<0.05)。결론문동안산갑미침제치료실성기전수축료효현저。
Objective To observe the clinical effect of potassium-magnesium aspartate injection in the treatment of ventricular premature contraction. Methods 86 patients with ventricular premature contraction > 4000 times by 24 h Holter monitoring were enrolled from January 2009 to January 2013,and were randomly divided into treatment group (50 cases) and control group (36 cases),the control group were treated with metoprolol,mexiletine,propafenoe,amiodarone and other routine anti-arrhythmic therapy,the treatment group were taken with potassium-magnesium aspartate injection on the basis of control group therapy.The changes of serum potassium,magnesium before and after treatment was moni-tored. Results After treatment,serum potassium,magnesium level of the treatment group had significant difference com-pared with before treatment (P<0.05,P<0.01);the control group had no significant difference (P>0.05);After treatment, serum potassium level of the treatment group was higher than that of the control group,the difference was significant (P<0.05),but serum magnesium level had no significant difference (P>0.05).The total effective rate of the treatment group was 78.00%,higher than 55.55% of the control group,the difference was significant (P<0.05). Conclusion The clinical effect of potassium-magnesium aspartate injection in treatment of ventricular premature contraction is remarkable.
