CAJ | 학술논문

目的：了解海南某三甲医院2013年抗菌药物使用情况，为临床合理使用和监管抗菌药物提供参考依据。方法采用回顾性调查分析方法，对该院2013年抗菌药物使用情况如日限定剂量（DDD）、住院患者抗菌药物使用率、抗菌药物使用强度等数据进行统计、分析。结果除门诊抗菌药物处方比例外，其他指标均达到了专项整治活动的目标要求；头孢菌素类销售金额、用药频度（DDDs）排序均居榜首；销售金额排名前10位的抗菌药物为注射剂型，均属β内酰胺类，且日用药金额（DDC）较高；DDDs排名前10位抗菌药物大多数为口服剂型，DDC较低。结论至2013年该院抗菌药物使用比例、强度、频率均得到有效控制，但尚存在广谱抗菌药物使用频率高、用药集中等问题，还需进一步加强监管。
목적：료해해남모삼갑의원2013년항균약물사용정황，위림상합리사용화감관항균약물제공삼고의거。방법채용회고성조사분석방법，대해원2013년항균약물사용정황여일한정제량（DDD）、주원환자항균약물사용솔、항균약물사용강도등수거진행통계、분석。결과제문진항균약물처방비예외，기타지표균체도료전항정치활동적목표요구；두포균소류소수금액、용약빈도（DDDs）배서균거방수；소수금액배명전10위적항균약물위주사제형，균속β내선알류，차일용약금액（DDC）교고；DDDs배명전10위항균약물대다수위구복제형，DDC교저。결론지2013년해원항균약물사용비례、강도、빈솔균득도유효공제，단상존재엄보항균약물사용빈솔고、용약집중등문제，환수진일보가강감관。
Objective To analyze the antibacterials application in a 3A-Grade Hospital in Hainan province in 2013 so as to provide reference for the follow-up management and standard use of antibiotics. Methods A retrospective statistical analysis was conducted on the antibiotic use of this hospital in 2013 with regard to DDDs,rate of antibiotic use in inpatients,antibiotic use intensity,etc. Results In addition to proportion of antibiotic use in outpatient,the other indicators reached the goal of the special rectification activity,eg,DDDs and sales amount of cephalosporin class ranked top;the dosage form that of the sales amount in the top ten of antibacterials was injections,belonging to beta-lactam,as well as the DDCs was higher,DDDs of the top ten of antibacte-rials that DDC is lower are most oral dosage forms. Conclusion The use proportion,indensity and frequence of the antibiotic a-gents were effectively controlled,but still there are many problems,such as over-centralized drug use,high use frequency of broad spectrum antibiotics,whose supervision and management should be strengthened further.