当代化工
噹代化工
당대화공
CONTEMPORARY CHEMICAL INDUSTRY
2015年
1期
21-23,26
,共4页
陈丽华%曹可生%彭勤龙%潘自红%马庆一
陳麗華%曹可生%彭勤龍%潘自紅%馬慶一
진려화%조가생%팽근룡%반자홍%마경일
山茱萸%知母%甘草%地榆%诃子%α-葡萄糖苷酶%抑制率
山茱萸%知母%甘草%地榆%訶子%α-葡萄糖苷酶%抑製率
산수유%지모%감초%지유%가자%α-포도당감매%억제솔
Cornus officinalis%Rhizoma anemarrhenaes%Licorice%Sanguisorba officinalis%Terminalia chebula ribs%α-glucosidase%Inhibition rate
从山茱萸、知母、甘草、地榆及诃子中提取水溶性多糖，并通过酶抑制动力学反应考察其对α-葡萄糖苷酶活性的影响。酶动力学反应结果表明：地榆多糖对α-葡萄糖苷酶有激活作用；知母多糖对α-葡萄糖苷酶的活性随时间的变化先激活后抑制；山茱萸多糖、甘草多糖及诃子多糖均对α-葡萄糖苷酶有抑制活性，其中抑制活性最好的是甘草多糖，其抑制率为72.5%；其各自的影响机理还有待进一步研究。
從山茱萸、知母、甘草、地榆及訶子中提取水溶性多糖，併通過酶抑製動力學反應攷察其對α-葡萄糖苷酶活性的影響。酶動力學反應結果錶明：地榆多糖對α-葡萄糖苷酶有激活作用；知母多糖對α-葡萄糖苷酶的活性隨時間的變化先激活後抑製；山茱萸多糖、甘草多糖及訶子多糖均對α-葡萄糖苷酶有抑製活性，其中抑製活性最好的是甘草多糖，其抑製率為72.5%；其各自的影響機理還有待進一步研究。
종산수유、지모、감초、지유급가자중제취수용성다당，병통과매억제동역학반응고찰기대α-포도당감매활성적영향。매동역학반응결과표명：지유다당대α-포도당감매유격활작용；지모다당대α-포도당감매적활성수시간적변화선격활후억제；산수유다당、감초다당급가자다당균대α-포도당감매유억제활성，기중억제활성최호적시감초다당，기억제솔위72.5%；기각자적영향궤리환유대진일보연구。
The water-soluble polysaccharide was extracted from Cornus officinalis,Rhizoma anemarrhenaes, Licorice, Sanguisorba officinalis and Terminalia chebula ribs. Influence of these water-soluble polysaccharides on the activity ofα-glucosidase was investigated by enzyme kinetics reaction. The results show that sanguisorba officinalis polysaccharide has the activation function to α-glucosidase;influence of Rhizoma anemarrhenae polysaccharide onα-glucosidase activity changes with time, activation first and then inhibition; Cornel polysaccharide, Licorice polysaccharide and Terminalia chebula ribs polysaccharide have inhibitory activities against α-glucosidase. Licorice polysaccharide shows the best α-glucosidase inhibitory activity of all, the inhibition rate can reach to 72.5 %.
