CAJ | 학술논문

目的：评价参麦萸术饮治疗小儿支气管哮喘的临床疗效及安全性。方法选取2012年5月~2013年4月本院收治的小儿支气管哮喘患者120例，随机分为观察组和对照组，其中对照组60例，采用抗生素等西医常规治疗，观察组60例，在对照组西医常规治疗的基础上加用中医辨证(参麦萸术饮)治疗，观察并比较两组患者临床疗效、肺功能指标及不良反应发生率。结果两组总有效率比较差异有统计学意义(P<0.05)；两组治疗后的PEF、FEV1相比治疗前均有明显改善，差异有统计学意义(P<0.05)；观察组治疗后的PEF及PEV1改善较对照组更明显，差异有统计学意义(P<0.05)；两组患者治疗过程中均未出现腹痛、腹泻、恶心、呕吐、心慌及皮疹等不良反应。结论在抗生素等常规西医治疗的基础上加用参麦萸术饮治疗小儿支气管哮喘的临床疗效好，肺功能指标改善明显，无明显不良反应发生，值得临床推广。
목적：평개삼맥유술음치료소인지기관효천적림상료효급안전성。방법선취2012년5월~2013년4월본원수치적소인지기관효천환자120례，수궤분위관찰조화대조조，기중대조조60례，채용항생소등서의상규치료，관찰조60례，재대조조서의상규치료적기출상가용중의변증(삼맥유술음)치료，관찰병비교량조환자림상료효、폐공능지표급불량반응발생솔。결과량조총유효솔비교차이유통계학의의(P<0.05)；량조치료후적PEF、FEV1상비치료전균유명현개선，차이유통계학의의(P<0.05)；관찰조치료후적PEF급PEV1개선교대조조경명현，차이유통계학의의(P<0.05)；량조환자치료과정중균미출현복통、복사、악심、구토、심황급피진등불량반응。결론재항생소등상규서의치료적기출상가용삼맥유술음치료소인지기관효천적림상료효호，폐공능지표개선명현，무명현불량반응발생，치득림상추엄。
Objective To evaluate clinical efficacy and safety of Shenmai Yuzhu decoction in the treatment of children with bronchial asthma. Methods 120 children with bronchial asthma from May 2012 to April 2013 in our hospital were selected and randomly divided into observation group and control group,antibiotics and other conventional western medicine treatment were used in control group(60 cases),syndrome differentiation with TCM(Shenmai Yuzhu decoction) was applied in observation group (60 cases) based on the treatment of control group.Clinical curative effect,the index of lung function and adverse reaction of two groups were observed and compared. Results Total effective rate in two groups was compared,with statistical difference(P<0.05).PEF and FEV1 in two groups after treatment was improved than that before treatment respectively,with statistical difference (P<0.05).PEF and FEV1 in observation group after treatment was improved than that in control group respectively,with statistical difference (P<0.05).Two groups of patients during treatment had no adverse reactions of abdominal pain,diarrhea,nausea,vomiting, lustered and rash. Conclusion Shenmai Yuzhu decoction in the treatment of children with bronchial asthma on the basis of antibiotics and other conventional western medicine therapy has good effect,pulmonary function index is improved significantly,without obvious adverse reaction,and is worthy of clinical promotion.