CAJ | 학술논문

目的：探讨神经内科营养神经药物辅助治疗脑梗死的临床效果及对同型半胱氨酸的影响。方法选取本院收治的138例脑梗死患者，按随机数字表法将患者均分为对照组(常规药物治疗)和观察组(在常规治疗的基础上加用神经节苷酯营养神经治疗)，比较两组患者的总有效率和治疗前后的同型半胱氨酸、叶酸水平。结果观察组的总有效率为94.2%，显著高于对照组的82.6%(P<0.05)；治疗后，观察组的同型半胱氨酸和叶酸水平优于对照组，差异有统计学意义(P<0.05)。结论神经内科营养神经药物辅助治疗脑梗死效果确切，可有效降低血同型半胱氨酸水平，有利于营养状态的维持及神经功能的恢复。
목적：탐토신경내과영양신경약물보조치료뇌경사적림상효과급대동형반광안산적영향。방법선취본원수치적138례뇌경사환자，안수궤수자표법장환자균분위대조조(상규약물치료)화관찰조(재상규치료적기출상가용신경절감지영양신경치료)，비교량조환자적총유효솔화치료전후적동형반광안산、협산수평。결과관찰조적총유효솔위94.2%，현저고우대조조적82.6%(P<0.05)；치료후，관찰조적동형반광안산화협산수평우우대조조，차이유통계학의의(P<0.05)。결론신경내과영양신경약물보조치료뇌경사효과학절，가유효강저혈동형반광안산수평，유리우영양상태적유지급신경공능적회복。
Objective To investigate clinical effect of neurotrophic drug of department of internal medicine for adju-vant treatment of cerebral infarction and the influence of drugs on homocysteine. Methods 138 cases with cerebral in-farction in our hospital were randomly divided into the control group (treated with conventional drugs) and observation group (treated with ganglioside neurotrophic therapy based on conventional drugs).The total effective rate,homocysteine and folate level before and after treatment of two groups were compared. Results The total effective rate of observation group was 94.2%,which was significantly higher than that of control group (82.6%) (P<0.05). Homocysteine and folate level after treatment of observation group were significantly better than that in the control group (P<0.05). Conclusion Neurotrophic drug for adjuvant treatment of cerebral infarction has exact efficacy.It can effectively reduce blood homo-cysteine levels.It is conducive to the maintenance of nutritional status and nerve function.