中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
1期
99-100,103
,共3页
孟鲁司特钠%布地奈德%外周血嗜酸粒细胞%小儿哮喘
孟魯司特鈉%佈地奈德%外週血嗜痠粒細胞%小兒哮喘
맹로사특납%포지내덕%외주혈기산립세포%소인효천
Montelukast sodium%Budesonide%Peripheral blood eosinophil%Asthma in children
目的：探讨孟鲁司特钠联合布地奈德治疗小儿哮喘的效果。方法选取2012年4月~2014年4月本院诊治的小儿哮喘患者共131例，将其随机分为对照组65例和治疗组66例。对照组单用布地奈德，治疗组加用孟鲁司特钠治疗。比较两组的疗效、肺功能和外周血Eos的变化情况。结果治疗组、对照组的总有效率分别为97.0%、87.7%，治疗组的总有效率高于对照组(P<0.05)；两组治疗后的肺功能指标(FEV1、PEF)和外周血Eos水平均优于治疗前(P<0.05)，且治疗组改善更显著(P<0.05)。结论孟鲁司特钠联合布地奈德治疗小儿哮喘可较好地恢复患儿的肺功能，明显改善其外周血Eos水平，效果显著，值得推广。
目的：探討孟魯司特鈉聯閤佈地奈德治療小兒哮喘的效果。方法選取2012年4月~2014年4月本院診治的小兒哮喘患者共131例，將其隨機分為對照組65例和治療組66例。對照組單用佈地奈德，治療組加用孟魯司特鈉治療。比較兩組的療效、肺功能和外週血Eos的變化情況。結果治療組、對照組的總有效率分彆為97.0%、87.7%，治療組的總有效率高于對照組(P<0.05)；兩組治療後的肺功能指標(FEV1、PEF)和外週血Eos水平均優于治療前(P<0.05)，且治療組改善更顯著(P<0.05)。結論孟魯司特鈉聯閤佈地奈德治療小兒哮喘可較好地恢複患兒的肺功能，明顯改善其外週血Eos水平，效果顯著，值得推廣。
목적：탐토맹로사특납연합포지내덕치료소인효천적효과。방법선취2012년4월~2014년4월본원진치적소인효천환자공131례，장기수궤분위대조조65례화치료조66례。대조조단용포지내덕，치료조가용맹로사특납치료。비교량조적료효、폐공능화외주혈Eos적변화정황。결과치료조、대조조적총유효솔분별위97.0%、87.7%，치료조적총유효솔고우대조조(P<0.05)；량조치료후적폐공능지표(FEV1、PEF)화외주혈Eos수평균우우치료전(P<0.05)，차치료조개선경현저(P<0.05)。결론맹로사특납연합포지내덕치료소인효천가교호지회복환인적폐공능，명현개선기외주혈Eos수평，효과현저，치득추엄。
Objective To investigate the effect of montelukast sodium combined with budesonide in the treatment of asthma in children. Methods 131 children with asthma diagnosed and treated in our hospital from April 2012 to April 2014 were chosen and they were randomly divided into the control group(n=65)and the treatment group(n=66).The con-trol group only was given budesonide,while the treatment group was given budesonide combined with montelukast sodi-um.The curative effect,the change of lung function and peripheral blood eosinophil in the two groups were compared. Results The total effective rate of the treatment group and the control group was 97.0%,87.7% respectively,the total ef-fective rate of the treatment group was higher than that in the control group (P<0.05);lung function indictors (FEV1,PEF) and the level of peripheral blood Eos of the two groups after treatment were better than before treatment (P<0.05),and the treatment group improved more significantly (P<0.05). Conclusion Montelukast sodium combined with budesonide in the treatment of asthma in children can better recover lung function of children,and obviously improve peripheral blood Eos leve.Its effect is significant,and it is worthy of promotion.
