CAJ | 학술논문

目的：了解本院药品不良反应(ADR)发生的规律和特点。方法抽取本院2012~2013年上报国家ADR监测中心的ADR报告162例，根据ADR表的内容，对患者年龄和性别，涉及ADR的药品种类，涉及ADR给药途径，ADR累及器官或系统及临床表现，转归等情况进行统计、分析。结果<18岁未成年人发生ADR的比例高达46.91%；静脉注射引起ADR居多，占87.65%；抗菌药物引起的ADR居多，占56.17%；ADR的临床表现多为皮肤及其附件受损，占48.15%。结论加强本院医务人员对ADR用药安全知识认识和宣传，进一步完善ADR报告奖惩制度，降低ADR发生率。
목적：료해본원약품불량반응(ADR)발생적규률화특점。방법추취본원2012~2013년상보국가ADR감측중심적ADR보고162례，근거ADR표적내용，대환자년령화성별，섭급ADR적약품충류，섭급ADR급약도경，ADR루급기관혹계통급림상표현，전귀등정황진행통계、분석。결과<18세미성년인발생ADR적비례고체46.91%；정맥주사인기ADR거다，점87.65%；항균약물인기적ADR거다，점56.17%；ADR적림상표현다위피부급기부건수손，점48.15%。결론가강본원의무인원대ADR용약안전지식인식화선전，진일보완선ADR보고장징제도，강저ADR발생솔。
Objective To know the rules and characteristics of adverse drug reactions (ADR) in our hospital. Methods 162 ADR cases reported to national ADR monitoring center from 2012 to 2013 in our hospital were selected.Referring to the contents in ADR list,the age,gender,drug category involved in ADR,administration route led to ADR,involved or-gans or systems due to ADR and their corresponding clinical manifestations,and prognosis were calculated and ana-lyzed. Results ADR occurred in young patients below 18 years old took a higher proportion accounting for 46.91%. ADR caused by intravenous injection took the majority and the percentage was 87.65%.Most ADR cases were ascribed to antibiotics with the proportion of 56.17%.The commonly-occurred clinical manifestations of ADR were injuries in skin and its attachment,which was 48.15%. Conclusion Acquaintance and promotion of knowledge about ADR medica-tion safety for medical staff in our hospital should be strengthened in order to further improve system of rewards and penalties in ADR report and reduce the incidence of ADR.