CAJ | 학술논문

近十余年来，我国原发性开角型青光眼（以下简称开青）患病率逐年上升，由0.29％上升到2.6％，一跃成为最重要的不可逆性致盲眼病。由于对开青眼压升高及视神经损害的机制认识不清，缺乏可行的筛查及有效的干预技术，其致盲率远高于发达国家8％的平均水平。王宁利教授所领导的项目组从回答开青眼压升高和视神经损害的关键科学问题入手，以解决开青筛查和监测的关键技术和设备为突破口，在阐明开青发病机制的基础上建立了基于机制的新分类体系，并在新理论、新分类基础上创建了新的开青筛查、诊断、监测和治疗技术，在全国范围内推广应用。覆盖人群1.2亿，实际受益患者320万人，减少因开青致盲约32万人，开青致盲率由15％下降到5％，减少开青致残约64万人，致残率由30％下降到15％。
근십여년래，아국원발성개각형청광안（이하간칭개청）환병솔축년상승，유0.29％상승도2.6％，일약성위최중요적불가역성치맹안병。유우대개청안압승고급시신경손해적궤제인식불청，결핍가행적사사급유효적간예기술，기치맹솔원고우발체국가8％적평균수평。왕저리교수소령도적항목조종회답개청안압승고화시신경손해적관건과학문제입수，이해결개청사사화감측적관건기술화설비위돌파구，재천명개청발병궤제적기출상건립료기우궤제적신분류체계，병재신이론、신분류기출상창건료신적개청사사、진단、감측화치료기술，재전국범위내추엄응용。복개인군1.2억，실제수익환자320만인，감소인개청치맹약32만인，개청치맹솔유15％하강도5％，감소개청치잔약64만인，치잔솔유30％하강도15％。
In the recent 1 0 years,the prevalence of primary open angle glaucoma(POAG)in China has been increased from 0.29%to 2.6%,and POAG becomes the most important irreversible blindness disease.As it is still in vague of the mechanism of intraocular pressure elevation and impairment of optic nerve,and lacks of screening and prevention technology,the blindness rate of POAG is higher than 8% which is the average level of developed country.Leading by Professor Ningli Wang,this program established the new POAG prevention and treatment system by resolving the mechanism of POAG and the key technology and instrument.The new technology and instrument has been applied in over 26 provinces and over 300 districts,which covered 1 20 million peoples.There are 3.2 million patients have been benefited from this program.The blindness rate of POAG has reduced from 1 5%to 5%,and the disable rate reduced from 30% to 1 5%.