医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2015年
5期
65-66
,共2页
人类免疫缺陷病毒%牙周致病菌%龈沟液%唾液
人類免疫缺陷病毒%牙週緻病菌%齦溝液%唾液
인류면역결함병독%아주치병균%간구액%타액
Human immunodeficiency virus%Periodontal pathogens%Gingival crevicular fluid%Saliva
目的了解云南地区部分HIV感染患者口腔内牙周致病菌检出情况。方法采用临床标本收集的方法，获得昆明市第三人民医院感染一科66例HIV感染者的唾液标本和龈沟液标本，通过DNA的提取和PCR检测，对标本中的6种牙周致病菌进行检测并运用统计学方法分析。结果不同细菌在不同取材标本都有检出，且各种细菌的检出率差异很大，但同一细菌在不同样本中检出率差异却极小。另外，吸烟饮酒、不同CD4细胞计数和高效抗逆转录病毒治疗(highly active anti retrovial therapy，HAART)HAART对可疑牙周致病菌的检出均无明显影响。结论应结合国内外的研究与报道，加强对HIV感染者口腔牙周致病菌的研究与检测，从而有针对性的治疗发生在HIV感染者口腔中的牙周疾病。
目的瞭解雲南地區部分HIV感染患者口腔內牙週緻病菌檢齣情況。方法採用臨床標本收集的方法，穫得昆明市第三人民醫院感染一科66例HIV感染者的唾液標本和齦溝液標本，通過DNA的提取和PCR檢測，對標本中的6種牙週緻病菌進行檢測併運用統計學方法分析。結果不同細菌在不同取材標本都有檢齣，且各種細菌的檢齣率差異很大，但同一細菌在不同樣本中檢齣率差異卻極小。另外，吸煙飲酒、不同CD4細胞計數和高效抗逆轉錄病毒治療(highly active anti retrovial therapy，HAART)HAART對可疑牙週緻病菌的檢齣均無明顯影響。結論應結閤國內外的研究與報道，加彊對HIV感染者口腔牙週緻病菌的研究與檢測，從而有針對性的治療髮生在HIV感染者口腔中的牙週疾病。
목적료해운남지구부분HIV감염환자구강내아주치병균검출정황。방법채용림상표본수집적방법，획득곤명시제삼인민의원감염일과66례HIV감염자적타액표본화간구액표본，통과DNA적제취화PCR검측，대표본중적6충아주치병균진행검측병운용통계학방법분석。결과불동세균재불동취재표본도유검출，차각충세균적검출솔차이흔대，단동일세균재불동양본중검출솔차이각겁소。령외，흡연음주、불동CD4세포계수화고효항역전록병독치료(highly active anti retrovial therapy，HAART)HAART대가의아주치병균적검출균무명현영향。결론응결합국내외적연구여보도，가강대HIV감염자구강아주치병균적연구여검측，종이유침대성적치료발생재HIV감염자구강중적아주질병。
Objective To understand the detection of oral periodontal pathogens in part of HIV infected patients in Yunnan region.Methods The col ection of clinic specimens were took to obtain the 66 cases of HIV infected patients,saliva and gingival crevicular fluid (GCF)samples which were come from the Third People,s of Kunming.The six kinds of periodontal pathogens were detected by extraction of DNA and PCR testing and analyzed by using statistical methods.Results The dif erent bacteria have been detected in dif erent specimens and the discrepancy of detection rate of these bacteria was significant.However,the dif erence of same bacterial in dif erent samples was minimal.In addition,there was no manifest function on the detection rate of periodontal pathogens in aspects of smoking,drinking,dif erent CD4 cel counts and highly active antiretroviral therapy(HAART).Conclusion It is vital to strengthen the research and detection of oral periodontal pathogens in HIV infected patients through combine with domestic and international research and report to treat targeted periodontal disease that occur ed in HIV infected patients.
