CAJ | 학술논문

目的：探讨256层CT冠状动脉成像时正常中青年国人左心室（ LV）整体功能正常值及其与性别、年龄的关系。方法410例LV整体功能分析指标包括舒张末期容积（ EDV）、收缩末期容积（ ESV）、每搏输出量（ SV）、每分心输出量（CO）、心肌质量（MM）、射血分数（EF）、标准化舒张末期容积（EDVI）、标准化收缩末期容积（ESVI）、标准化每搏输出量（SVI）、心脏指数（CI）、心肌质量指数（MMI）正常值，观察性别间心功能参数差异、心功能与体重指数（body mass index，BMI）及年龄之间的相关性。结果 LV整体功能参数，男性为：ESV 47 I．10～55．33 ml，EDV 143．15～154．56 ml，SV 94．49～102．96 ml，CO 6162．59～6734．39 ml／min，MM 129．78～146．00 g，EF 64．17％～67．69％；女性为：ESV 39．62～45．33 ml／m2， EDV 126．49～136．26 ml／m2， SV 85．43～92．35 ml／m2， CI 5590．52～6129．45 ml· min－1· m－2，MM 101．98～113．87 g／m2，EF 65．87％～69．00％。男性组LV整体功能参数值明显高于女性组，标准化后，仅MMI较高。 BMI与左心室整体功能参数相关性：EDV、ESV、SV、CO、MM与BMI呈正相关（ r值分别为0．2930、．424、0．335、0．199、0．482）。标准化后MMI与BMI呈负相关（ r ＝0．276， P ＜0．05），EDVI、ESVI、SVI、CI与BMI无相关性。年龄与LV整体功能参数：EDV、 ESV与年龄呈负相关（ r ＝－0．362，－0．436， P ＜0．05）。结论256层CT可方便地获得正常中青年人LV整体功能MSCT参数，各参数与性别及年龄、BMI有一定关系。
목적：탐토256층CT관상동맥성상시정상중청년국인좌심실（ LV）정체공능정상치급기여성별、년령적관계。방법410례LV정체공능분석지표포괄서장말기용적（ EDV）、수축말기용적（ ESV）、매박수출량（ SV）、매분심수출량（CO）、심기질량（MM）、사혈분수（EF）、표준화서장말기용적（EDVI）、표준화수축말기용적（ESVI）、표준화매박수출량（SVI）、심장지수（CI）、심기질량지수（MMI）정상치，관찰성별간심공능삼수차이、심공능여체중지수（body mass index，BMI）급년령지간적상관성。결과 LV정체공능삼수，남성위：ESV 47 I．10～55．33 ml，EDV 143．15～154．56 ml，SV 94．49～102．96 ml，CO 6162．59～6734．39 ml／min，MM 129．78～146．00 g，EF 64．17％～67．69％；녀성위：ESV 39．62～45．33 ml／m2， EDV 126．49～136．26 ml／m2， SV 85．43～92．35 ml／m2， CI 5590．52～6129．45 ml· min－1· m－2，MM 101．98～113．87 g／m2，EF 65．87％～69．00％。남성조LV정체공능삼수치명현고우녀성조，표준화후，부MMI교고。 BMI여좌심실정체공능삼수상관성：EDV、ESV、SV、CO、MM여BMI정정상관（ r치분별위0．2930、．424、0．335、0．199、0．482）。표준화후MMI여BMI정부상관（ r ＝0．276， P ＜0．05），EDVI、ESVI、SVI、CI여BMI무상관성。년령여LV정체공능삼수：EDV、 ESV여년령정부상관（ r ＝－0．362，－0．436， P ＜0．05）。결론256층CT가방편지획득정상중청년인LV정체공능MSCT삼수，각삼수여성별급년령、BMI유일정관계。
Objective To setup the normal range of left ventricular ( LV) global function parameters in healthy young and middle-aged people,and to explore the relationship between the gender ,age,body mass index(BMI)and LV global function parameters .All these cases did not detect any abnormalities about coronary and heart when having coronary artery CTA with 256 slice CT.Methods To the 410 normal cases, end-diastolic volume ( EDV), end-systolic volume ( ESV), stroke volume(SV),ejection fraction(EF),cardiac output(CO), myocardial mass(MM),end-diastolic volume index(EDVI), end-systolic volume index(ESVI),stroke volume index(SVI),cardiac output index(CI),myocardial mass index(MMI) were measured .The difference of the parameters between the two genders ,the relationship between the LV global function parameters and BMI,age were evaluated.Resu lts The normal range of left ventricular ( LV) global function are:male,ESV47.10 ~55.33ml,EDV143.15~154.56ml ,SV 94.49~102.96ml,CO 6162.59~6734.39ml/min,MM 129.78~146.00g,EF 64.17~67.69%.Female:ESV 39.62~45.33ml,EDV 126.49~136.26ml,SV 85.43~92.35ml,CI 5590.52~6129.45ml/min, MM 101.98~113.87g,EF 65.87%~69.00%.EDV,ESV,SV,CO,MM in male group are significantly higher than those in female group( P <0.05).Wheras,for the standardized parameters,only MMI in male group is larger than that in female group ( P <0.05).There is no correlation between BMI and EF ( P =0.194),while there are definitive correlation between BMI and EDV,ESV,SV,CO,MM ( P =0.002,0.000,0.000,0.038,0 .000, r =0.293,0.424,0.335,0.199,0.482 ).After standardization,only MMI is correlated with BMI,( P =0.04, r =0.276).Age is significantly correlated with ESV and EDV ( P =0.017,0.003,r =-0.362,-0.436) before standardization.But,after standardization,there is no correlation between the age and all parameters .Conclusion It is convenience to get the normal range of left ventricular ( LV) global function parameters in healthy young and middle-aged people when having coronary CTA with 256-slice CT.There is certain correlation between these parameters and genders ,age,as well as BMI .