CAJ | 학술논문

利用自主研制的高灵敏呼气检测质子转移反应质谱( PTR-MS)，对一名口臭受试者的口腔吹出气体、鼻子呼出气体和口腔内气体分别进行多组分实时监测，发现了该受试者呼气中3种引起口臭的挥发性硫化物( VSCs)的来源并不相同，其中甲硫醇主要来源于口腔，硫化氢和二甲基硫则主要来源于肺或呼吸道。本研究不仅发现了口腔内气体在PTR-MS呼气监测过程中的特征变化趋势，还分析了呼出气体中3种VSCs的来源，对于呼气的正确采样和检测具有重要的指导意义。
이용자주연제적고령민호기검측질자전이반응질보( PTR-MS)，대일명구취수시자적구강취출기체、비자호출기체화구강내기체분별진행다조분실시감측，발현료해수시자호기중3충인기구취적휘발성류화물( VSCs)적래원병불상동，기중갑류순주요래원우구강，류화경화이갑기류칙주요래원우폐혹호흡도。본연구불부발현료구강내기체재PTR-MS호기감측과정중적특정변화추세，환분석료호출기체중3충VSCs적래원，대우호기적정학채양화검측구유중요적지도의의。
To develop a kind of noninvasive method of breath diagnosis in diseases, much attention has been paid to the study of the relation between diseases and volatile organic compounds in human breath gas. However, the gas in oral cavity was usually ignored in many studies of breath gas. The bad breath odor of a participant was studied by a home-made proton transfer reaction mass spectrometer( PTR-MS) . The breath via the mouth, breath via the nose and the air in the mouth cavity were monitored with the mode of multiple ion detect scans. The results show that three different volatile sulfur compounds that cause bad breath odor should be attributed to different sources. The source of methyl mercaptan in breath is oral cavity, and the source of hydrogen sulphide and dimethylsulfide in breath is lung or respiratory tract. The related result is very important to sampling and detection of breath gas.