高等学校化学学报
高等學校化學學報
고등학교화학학보
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES
2015年
2期
201-211
,共11页
王建勋%秦四勇%蔡腾腾%张先正%卓仁禧
王建勛%秦四勇%蔡騰騰%張先正%卓仁禧
왕건훈%진사용%채등등%장선정%탁인희
两亲性多肽%自组装%形貌%纳米结构%生物功能材料
兩親性多肽%自組裝%形貌%納米結構%生物功能材料
량친성다태%자조장%형모%납미결구%생물공능재료
Amphiphilic peptide%Self-assembly%Morphology%Nano structure%Biological functional material
两亲性多肽分子具有类似天然磷脂分子的两亲特性、丰富的分子结构、独特新颖的组装体结构以及特殊的生物学功能,是多肽自组装研究的热点领域。本文总结了近年来关于两亲性多肽自组装研究及应用的进展,介绍了几种常见的两亲性多肽,并进一步阐述其分子结构特征、组装行为和机理、组装体结构和功能以及在纳米技术和生物医学领域中的应用。
兩親性多肽分子具有類似天然燐脂分子的兩親特性、豐富的分子結構、獨特新穎的組裝體結構以及特殊的生物學功能,是多肽自組裝研究的熱點領域。本文總結瞭近年來關于兩親性多肽自組裝研究及應用的進展,介紹瞭幾種常見的兩親性多肽,併進一步闡述其分子結構特徵、組裝行為和機理、組裝體結構和功能以及在納米技術和生物醫學領域中的應用。
량친성다태분자구유유사천연린지분자적량친특성、봉부적분자결구、독특신영적조장체결구이급특수적생물학공능,시다태자조장연구적열점영역。본문총결료근년래관우량친성다태자조장연구급응용적진전,개소료궤충상견적량친성다태,병진일보천술기분자결구특정、조장행위화궤리、조장체결구화공능이급재납미기술화생물의학영역중적응용。
Due to good biocompatibility, straight forward chemical modification and inherent molecular recog-nition, peptides have been very attractive biological building blocks for self-assembly. Amphiphilic peptides are of special interesting with the advantages of abundant molecular structures, unique structures of assemblies and special biological functions. In this work, the recent progress in the study and application of the self-assembly of amphiphilic peptides was reviewed. Several kinds of amphiphilic peptides were introduced. More-over, the molecular structures of amphiphilic peptides, the behavior and mechanism of self-assembly, the structure and property of assemblies and their applications in nanotechnology and biomedical field were also demonstrated in detail.