CAJ | 학술논문

动脉粥样硬化是一种慢性血管壁炎症性疾病，导致血管损伤或斑块的形成，其特征是炎性细胞浸润。冠状动脉粥样硬化性心脏病（冠心病）是由冠状动脉粥样硬化致心肌缺血缺氧或坏死而引起的心脏病。目前有很多研究证实，冠心病与炎性因子和免疫有关，而与炎症和免疫有关的因子很多。目前有一些新的生物指标如：组织蛋白酶K、脂蛋白相关磷脂酶 A2、缺血修饰白蛋白、和肽素等。这些因子对冠心病的预后和危险分层等起着重要的作用。
동맥죽양경화시일충만성혈관벽염증성질병，도치혈관손상혹반괴적형성，기특정시염성세포침윤。관상동맥죽양경화성심장병（관심병）시유관상동맥죽양경화치심기결혈결양혹배사이인기적심장병。목전유흔다연구증실，관심병여염성인자화면역유관，이여염증화면역유관적인자흔다。목전유일사신적생물지표여：조직단백매K、지단백상관린지매 A2、결혈수식백단백、화태소등。저사인자대관심병적예후화위험분층등기착중요적작용。
Atherosclerosis is a chronic inflammatory disorder of the vessel wall ,resulting in formation of vascular lesions,or plaques,which are characterised by inflammation .Coronary heart disease is a clinical syn-drome which caused by myocardial ischemia or necrosis .There are many studies have confirmed coronary heart disease is associated with inflammation and immunity,there are many inflammatory factors.At present, there are some novel biomarkers such as:cathepsin K,lipoprotein associated phospholipase A2(Lp-PLA2), Ischemia Modiffied Albumin(IMA),and copeptin.These factors play an important role in the prognosis of coronary heart disease and risk stratification .