CAJ | 학술논문

目的：探讨反复输血后不完全抗体的阳性率及其临床意义。方法选取2010年12月至2012年7月来海口市人民医院的1498例反复申请输血者作为研究对象，另选择同期1500例首次输血者作为对照组。采用DiaMcd微柱凝胶免疫技术（ IgG卡）对申请输血者的血液标本进行不规则抗体筛查，同时对不规则抗体阳性的标本进行抗体鉴定。结果反复输血者的不完全抗体阳性率为3．07％（46／1498），而首次输血者的不完全抗体阳性率为0．27％（4／1498），两者比较差异有统计学意义（P＜0．05）。46例反复输血者以抗-E抗体阳性最多，为22例，占47．8％。结论重视受血者不完全抗体的检测对预防和减少输血不良反应、保证输血安全有重要意义。
목적：탐토반복수혈후불완전항체적양성솔급기림상의의。방법선취2010년12월지2012년7월래해구시인민의원적1498례반복신청수혈자작위연구대상，령선택동기1500례수차수혈자작위대조조。채용DiaMcd미주응효면역기술（ IgG잡）대신청수혈자적혈액표본진행불규칙항체사사，동시대불규칙항체양성적표본진행항체감정。결과반복수혈자적불완전항체양성솔위3．07％（46／1498），이수차수혈자적불완전항체양성솔위0．27％（4／1498），량자비교차이유통계학의의（P＜0．05）。46례반복수혈자이항-E항체양성최다，위22례，점47．8％。결론중시수혈자불완전항체적검측대예방화감소수혈불량반응、보증수혈안전유중요의의。
Objective To explore the incomplete antibody positive rate and clinical significance of the patients who have been transfused time after time. Methods Total of 1498 cases of transfusion patients from Haikou people's hospital during December 2010 to July 2012 were selected as the research objects,and 1500 cases of blood transfusion for the first time were selected as control group. The blood preparations of blood transfusion patients were screening by immune DiaMcd micro-column gel technology ( IgG), and car-ried out antibody identification for the irregular antibody positive of specimens at the same time.Results The incomplete antibody positive rate of 1498 repeated blood transfusion was 3.07%(46/1498),and 0.27%(4/1498)of 1500 patients with first blood transfusion,there were statistical significance differencesbetween the two group(P <0.05).The Anti-E antibody positive rate of 46 repeated blood transfusion patientsis 47.8%(22/46).Conclusion Clinical must attaches great importance to detection of blood recipients,its important for prevention and reduce the adverse reaction,ensure the safety of blood transfusion.