CAJ | 학술논문

目的：探讨早发型和晚发型重度子痫前期的分娩方式及妊娠结局。方法选取2011年1月至2013年6月在渭南市中心医院产科治疗的重度子痫前期患者324例，以发病孕周34周为分界点分为两组：早发型组（孕周＜34周）96例，晚发型组（孕周≥34周）228例。比较两组分娩方式及母婴结局。结果早发型组患者分娩孕周早于晚发型[（31．6±2．1）周 vs （37．9±2．7）周，P ＜0．05]；早发型组治疗时间长于晚发组[（8．4±4．5） d vs （2．7±1．4） d，P＜0．05]；早发型组剖宫产率高于晚发型组（57．3％ vs 36．0％，P ＜0．05）；早发型组利凡诺引产率高于晚发型组（12．5％ vs 1．3％，P＜0．05）；早发型组自然分娩率低于晚发型组（25．0％ vs 50．4％，P＜0．05）。早发型组母体并发症的发生率以及新生儿窒息率、胎儿生长受限、低出生体质量儿发生率、转婴儿重症监护病房率和围生儿病死率均显著高于晚发型组（45．8％ vs 11．0％，37．5％ vs 4．8％，12．5％ vs 2．6％，53．1％ vs 25．0％，38．5％vs 15．8％，16．7％vs 3．5％，P＜0．05）。结论子痫前期患者的分娩方式以剖宫产为主，早发型子痫前期较晚发型子痫前期病情严重，预后不佳。
목적：탐토조발형화만발형중도자간전기적분면방식급임신결국。방법선취2011년1월지2013년6월재위남시중심의원산과치료적중도자간전기환자324례，이발병잉주34주위분계점분위량조：조발형조（잉주＜34주）96례，만발형조（잉주≥34주）228례。비교량조분면방식급모영결국。결과조발형조환자분면잉주조우만발형[（31．6±2．1）주 vs （37．9±2．7）주，P ＜0．05]；조발형조치료시간장우만발조[（8．4±4．5） d vs （2．7±1．4） d，P＜0．05]；조발형조부궁산솔고우만발형조（57．3％ vs 36．0％，P ＜0．05）；조발형조리범낙인산솔고우만발형조（12．5％ vs 1．3％，P＜0．05）；조발형조자연분면솔저우만발형조（25．0％ vs 50．4％，P＜0．05）。조발형조모체병발증적발생솔이급신생인질식솔、태인생장수한、저출생체질량인발생솔、전영인중증감호병방솔화위생인병사솔균현저고우만발형조（45．8％ vs 11．0％，37．5％ vs 4．8％，12．5％ vs 2．6％，53．1％ vs 25．0％，38．5％vs 15．8％，16．7％vs 3．5％，P＜0．05）。결론자간전기환자적분면방식이부궁산위주，조발형자간전기교만발형자간전기병정엄중，예후불가。
Objective To analyze the mode delivery and perinatal outcomes of two conditions ( early and late-onset pre-eclampsia) .Methods A retrospective research was conducted to assess the mode deliver-y,complications and neonatal mortality among 324 pre-eclampsia (96 early onset,228 late onset) between Jan 2011 and Jun 2013.Results The terminated gestation ages of early onset patients is significantly earlier than that in late onset patients[(31.6 ±2.1) week vs (37.86 ±2.7)week,P<0.05].The treatment time of early onset patients is significantly longer than that in late onset patients[(8.4 ±4.5) d vs (2.7 ±1.4) d,P<0.05].The caesarean section rate of early onset patients was higher than that of late onset patients (57.3% vs 36.0%,P<0.05).The rivanol induced labor rate of early onset patients was higher than that of late onset patients(12.5% vs 1.3%,P<0.05); The natural labor rate of early onset patients was lower than that of late onset patients(25.0% vs 50.4%,P<0.05).The incidence rate of maternal complications and newborn asphyxia, fetal growth restriction, low birth weight infant, shifting to intensive care unit, neo-natal death in early onset group were significantly higher than that in late onset group (45.8%vs11.0%,37. 5% vs 4.8%, 12.5% vs 2.6%, 53.1% vs 25.0%, 38.5% vs 15.8%, 16.7% vs 3.5%, P<0.05). Conclusion Caesarean section was a major mode delivery for pre-eclampsia;maternal and neonatal adverse outcomes were higher in early onset pre-eclampsia.