CAJ | 학술논문

角蛋白酶（ keratinase）是一种可以特异性降解角蛋白的酶类，其来源广泛，多种微生物在羽毛降解过程中均可产生角蛋白酶。不同菌种来源的角蛋白酶，其结构、理化性质、活性和底物也不同。其在饲料行业、制革工业和环境废弃物处理等多个方面具有广泛的应用前景，能够产生巨大的社会效益和经济效益。本文系统总结了角蛋白酶的来源、分类、理化性质、作用机理及其在基因工程研究等方面的一些最新进展，简要介绍了其应用研究现状，并展望了角蛋白酶的应用前景。
각단백매（ keratinase）시일충가이특이성강해각단백적매류，기래원엄범，다충미생물재우모강해과정중균가산생각단백매。불동균충래원적각단백매，기결구、이화성질、활성화저물야불동。기재사료행업、제혁공업화배경폐기물처리등다개방면구유엄범적응용전경，능구산생거대적사회효익화경제효익。본문계통총결료각단백매적래원、분류、이화성질、작용궤리급기재기인공정연구등방면적일사최신진전，간요개소료기응용연구현상，병전망료각단백매적응용전경。
Keratinase is kind of specific enzyme that can degrade keratin.It derives from a wealth of sources.A variety of microorganisms can produce keratinase in the process of feather degradation.Keratinases from different strains are different in structure, physical and chemical properties, activity and also substrate.Keratinase has broad application prospects in feed industry, leather industry, and environmental waste disposal, etc., which bring enormous social and economic benefits.This paper summarizes research progress on keratinase in physicochemical properties, enzymatic mechanisms, sources and classification, as well as genetic engineering, introduces the status of keratinase application and finally proposes the application prospects.