CAJ | 학술논문

目的：分析女性乳腺密度的构成与生理、生育因素及乳腺癌之间相关性。方法选取接受全数字乳腺X射线摄影检查且临床资料完整的当地女性5006例，以ACR BI－RADS标准，依据乳腺X射线摄影结果评价乳腺腺体密度类型，乳腺癌以病理诊断为标准。按不同年龄、生育特征因素分组，分析其与乳腺密度构成及乳腺癌之间相关性。结果5006例中受检查年龄（44．22±8．09）岁，中位年龄43岁。乳腺密度构成为脂肪型256例（5.11％），少量型726例（14．51％），多量型3719例（74．29％），致密型305例（6．09％）。乳腺密度与年龄、哺乳史、流产史、绝经年龄、绝育手术有相关性，与初潮年龄、初产年龄、服用雌激素无相关性。病理证实乳腺癌184例，其乳腺密度构成为脂肪型26例（14．13％），少量型91例（49．46％），多量型91例（49．46％），致密型1例（0．54％）。乳腺癌患者乳腺密度与年龄、绝经年龄、服用雌激素有相关性，与初潮年龄、初产年龄、哺乳史、流产史、绝育手术无相关性。结论年龄、哺乳史、流产史、绝经年龄、是否做过绝育手术是影响女性乳腺密度的重要因素，绝经期前后女性以及较低乳腺密度类型女性患乳腺癌风险更突出。
목적：분석녀성유선밀도적구성여생리、생육인소급유선암지간상관성。방법선취접수전수자유선X사선섭영검사차림상자료완정적당지녀성5006례，이ACR BI－RADS표준，의거유선X사선섭영결과평개유선선체밀도류형，유선암이병리진단위표준。안불동년령、생육특정인소분조，분석기여유선밀도구성급유선암지간상관성。결과5006례중수검사년령（44．22±8．09）세，중위년령43세。유선밀도구성위지방형256례（5.11％），소량형726례（14．51％），다량형3719례（74．29％），치밀형305례（6．09％）。유선밀도여년령、포유사、유산사、절경년령、절육수술유상관성，여초조년령、초산년령、복용자격소무상관성。병리증실유선암184례，기유선밀도구성위지방형26례（14．13％），소량형91례（49．46％），다량형91례（49．46％），치밀형1례（0．54％）。유선암환자유선밀도여년령、절경년령、복용자격소유상관성，여초조년령、초산년령、포유사、유산사、절육수술무상관성。결론년령、포유사、유산사、절경년령、시부주과절육수술시영향녀성유선밀도적중요인소，절경기전후녀성이급교저유선밀도류형녀성환유선암풍험경돌출。
Objective It is to analyze the relevance between the structure of female breast density and physiology, repro-ductive characteristics and breast cancer.Methods 5006 cases of local women with complete data whom had accepted digital breast X-ray angiography were selected.ACR BI-RADS was used as standard to evaluate mammary gland density type.Be-sides, breast cancer was diagnosed on the basis of pathological diagnosis.In the study, all data was divided according to phys-iology and reproductive characteristics, and the composing and correlation between breast cancer and breast density was ana-lyzed.Results The average age was 44.22 ±8.09 and median age was 43.Constitution of the mammary gland density in 5 006:lard type 256(5.11%), small type 726(14.51%), quantity type 3719(74.29%), and density type 305(6.09%).There was statistically significant difference between breast density and age, lactation history, history of abortion, menopause age, sterilization etc(P<0.01), while there was no statistically significant difference between breast density and menarche age, first delivery, whether take strogen etc(P>0.05).Pathology confirmed breast cancer 184 cases, constitution of the mammary gland density:lard type 26(14.13%), small type 66(35.87%), quantity type 91(49.46%)and density type 1(0.54%). Significant statistically difference was found between mammary gland density and age, menopause age, whether take strogen etc(P<0.01).However, there was no statistically significant difference between breast density and menarche age, first deliv-ery age, lactation history, history of abortion, sterilization etc(P>0.05).Conclusion The important factors that affect female breast density showing as follows:age, lactation history, history of abortion, menopause age, whether done sterilization, nev-ertheless, age, menopause women and low density of breast could increase the risk .