基层医学论坛
基層醫學論罈
기층의학론단
PUBLIC MEDICAL FORUM MAGAZINE
2015年
1期
4-7
,共4页
妊娠高血压综合征%强化利尿%APACHEⅡ评分%死亡风险
妊娠高血壓綜閤徵%彊化利尿%APACHEⅡ評分%死亡風險
임신고혈압종합정%강화이뇨%APACHEⅡ평분%사망풍험
Pregnancy-induced hypertension%Aggressive diuretic therapy%APACHE-Ⅱscore%Mortality risk
目的：评价强化利尿对降低产后重度妊娠高血压综合征患者（简称妊高征）死亡风险的作用。方法将2009年1月1日—2013年10月30日入我院ICU的产后重度妊高征患者随机分为强化利尿组（48例）和对照组（46例），比较2组治疗前后及组间急性生理与慢性健康状况（APACHEⅡ）评分、死亡风险系数、日均尿量、ICU停留时间等临床指标。结果同对照组相比，强化利尿组日均尿量显著增加（P<0.05）；患者血压、肺部氧合、肾功能显著改善，达到利尿终点时间、ICU停留时间显著缩短（P<0.05）；强化利尿组APACHEⅡ评分显著下降，死亡风险系数低于对照组（P<0.05）。结论重度妊高征患者产后强化利尿治疗可使病情较快恢复，并有助于降低重度妊高征患者产后死亡风险。
目的：評價彊化利尿對降低產後重度妊娠高血壓綜閤徵患者（簡稱妊高徵）死亡風險的作用。方法將2009年1月1日—2013年10月30日入我院ICU的產後重度妊高徵患者隨機分為彊化利尿組（48例）和對照組（46例），比較2組治療前後及組間急性生理與慢性健康狀況（APACHEⅡ）評分、死亡風險繫數、日均尿量、ICU停留時間等臨床指標。結果同對照組相比，彊化利尿組日均尿量顯著增加（P<0.05）；患者血壓、肺部氧閤、腎功能顯著改善，達到利尿終點時間、ICU停留時間顯著縮短（P<0.05）；彊化利尿組APACHEⅡ評分顯著下降，死亡風險繫數低于對照組（P<0.05）。結論重度妊高徵患者產後彊化利尿治療可使病情較快恢複，併有助于降低重度妊高徵患者產後死亡風險。
목적：평개강화이뇨대강저산후중도임신고혈압종합정환자（간칭임고정）사망풍험적작용。방법장2009년1월1일—2013년10월30일입아원ICU적산후중도임고정환자수궤분위강화이뇨조（48례）화대조조（46례），비교2조치료전후급조간급성생리여만성건강상황（APACHEⅡ）평분、사망풍험계수、일균뇨량、ICU정류시간등림상지표。결과동대조조상비，강화이뇨조일균뇨량현저증가（P<0.05）；환자혈압、폐부양합、신공능현저개선，체도이뇨종점시간、ICU정류시간현저축단（P<0.05）；강화이뇨조APACHEⅡ평분현저하강，사망풍험계수저우대조조（P<0.05）。결론중도임고정환자산후강화이뇨치료가사병정교쾌회복，병유조우강저중도임고정환자산후사망풍험。
Objective To evaluate the role of aggressive diuretic therapy to reduce mortality risk of postnatal patients with severe PIH (pregnancy-induced hypertension,PIH) in ICU. Methods 94 postnatal patients with severe PIH admitted to the ICU of the First Affiliated Hospital ,University of South China from January 1st, 2009 to October 30, 2013, Who were randomly divided into two groups:the control group (n=46) and the aggressive diuretic therapy group (n=48).APACHE-Ⅱscores, mortality risk coefficients,average daily urine output, and length of ICU stay were compared between the control group and the aggressive diuretic therapy group. Results The average daily urine output of patients in aggressive diuretic therapy group increased when compared with that in control group (P<0.05).Blood pressure, oxygenation index (PaO2,PaO2/FiO2) and renal function of the patients in aggressive diuretic therapy group improved by comparison of control group(all P<0.05),and length of diuretic therapy and length of ICU stay of the patients in aggressive diuretic therapy group decreased significantly (P<0.05).Compared with control group, APACHE-Ⅱscores and mortality risk coefficients of the patients in aggressive diuretic therapy group decreased significantly after diuretic therapy(P<0.05). Conclusions Aggressive diuretic therapy in postnatal patients with severe PIH is conducive to recovery from disease quickly. Moreover it may contribute to reduce the mortality risk of postnatal patients with severe PIH.
