CAJ | 학술논문

目的：制备骨愈搽剂并对其质量进行检查。方法：根据前期工艺研究结果进行中试生产制备骨愈搽剂，采用紫外分光光度法测定骨愈搽剂中总黄酮含量；采用薄层色谱法鉴别鸡血藤、伸筋草、花椒；进行装量差异、相对密度、pH值、微生物、稳定性等项目的检查。结果：中试提取条件为70％乙醇，10倍量，回流1 h，提取3次；鸡血藤、伸筋草、花椒照薄层色谱法，点样于硅胶G薄层板，展开，检视，均与对照品色谱相应位置上显相同颜色的荧光斑点；以芦丁为对照品，采用紫外分光光度法，在511 nm处测定骨愈搽剂中总黄酮含量为6．95 g／瓶；装量差异符合相关要求；样品在室温下留样观察，在6个月内质量稳定。结论：本制剂制备工艺简便，质量稳定可控。
목적：제비골유차제병대기질량진행검사。방법：근거전기공예연구결과진행중시생산제비골유차제，채용자외분광광도법측정골유차제중총황동함량；채용박층색보법감별계혈등、신근초、화초；진행장량차이、상대밀도、pH치、미생물、은정성등항목적검사。결과：중시제취조건위70％을순，10배량，회류1 h，제취3차；계혈등、신근초、화초조박층색보법，점양우규효G박층판，전개，검시，균여대조품색보상응위치상현상동안색적형광반점；이호정위대조품，채용자외분광광도법，재511 nm처측정골유차제중총황동함량위6．95 g／병；장량차이부합상관요구；양품재실온하류양관찰，재6개월내질량은정。결론：본제제제비공예간편，질량은정가공。
Objective:To prepare the Guyu liniment and to establish the quality control method for this medicine.Methods:Ac-cording to the previous studies to prepare the Guyu liniment, UV spectrophotometry was used to determine the content of total fla-vonoids in Guyu liniment.TLC was used to identify Spatholobi Caulis, Lycopodii Herba and Zanthoxyli Pericarpium in the pre-scription of Guyu liniment.The content uniformity, relative density, pH, microbe and stability of Guyu liniment were measured. Results:The preparation technology of Guyu liniment is simple.The quality of Guyu liniment is stable and controllable.