医学美学美容（中旬刊）
醫學美學美容（中旬刊）
의학미학미용（중순간）
MEDICAL AESTHETICS AND COSMETOLOGY
2015年
1期
24-24
,共1页
手足口病%神经源性肺水肿%肺微血管内皮细胞%Bcl-2%Bax
手足口病%神經源性肺水腫%肺微血管內皮細胞%Bcl-2%Bax
수족구병%신경원성폐수종%폐미혈관내피세포%Bcl-2%Bax
Hand foot and mouth disease%Neurogenic pulmonary edema%Pulmonary microvascular endothelial cel s%Bcl-2%Bax
近几年来手足口病在全球的发病率非常高，重症手足口病并发神经源性肺水肿（neurogenic pulmonary edema，NPE）起病急，病情发展快，病死率较高。NPE与肺微血管内皮细胞凋亡有关。Bcl－2和Bax是Bcl－2家族中与细胞凋亡关系密切的两种基因，前者为抗凋亡基因，后者为促凋亡基因。Bcl－2、Bax的表达可能与NPE的发病有关。
近幾年來手足口病在全毬的髮病率非常高，重癥手足口病併髮神經源性肺水腫（neurogenic pulmonary edema，NPE）起病急，病情髮展快，病死率較高。NPE與肺微血管內皮細胞凋亡有關。Bcl－2和Bax是Bcl－2傢族中與細胞凋亡關繫密切的兩種基因，前者為抗凋亡基因，後者為促凋亡基因。Bcl－2、Bax的錶達可能與NPE的髮病有關。
근궤년래수족구병재전구적발병솔비상고，중증수족구병병발신경원성폐수종（neurogenic pulmonary edema，NPE）기병급，병정발전쾌，병사솔교고。NPE여폐미혈관내피세포조망유관。Bcl－2화Bax시Bcl－2가족중여세포조망관계밀절적량충기인，전자위항조망기인，후자위촉조망기인。Bcl－2、Bax적표체가능여NPE적발병유관。
In recent years,the incidence rate of hand foot and mouth disease is very high in the global,severe hand foot and mouth disease could be complicated by neurogenic pulmo-nary edema had onset nasty,il ness development quickly,high fatality rate.NPE is associated with apoptosis of pulmonary microvascular endothelial cel .Bcl-2 gene and Bax gene is closely as-sociated with apoptosis in the Bcl-2 family ,the former for antiapoptotic genes,the lat er to promote apoptosis gene.the expression of Bcl-2 gene and Bax gene may be associated with the onset of NPE.
