医学美学美容（中旬刊）
醫學美學美容（中旬刊）
의학미학미용（중순간）
MEDICAL AESTHETICS AND COSMETOLOGY
2015年
1期
71-72
,共2页
兔%VX2肝移植瘤%影像表现
兔%VX2肝移植瘤%影像錶現
토%VX2간이식류%영상표현
rabbit%VX2 liver transplantation tumor%imaging features
目的：建立兔VX2肝移植瘤模型，对其影像学表现进行评价，为下一步联合壁虎活性单体评价治疗效果提供一定的参考。方法：20只兔新西兰大白兔在无菌条件下接种VX2瘤组织块，建立VX2肝移植瘤模型，2周后行超声、3．0T磁共振，评价其影像表现。结果：成瘤率为90％。超声表现为略高回声团块，没有包膜，其内可见强回声。TIWI表现为低信号，T2WI表现为高信号，增强扫描后明显强化，内部有不强化的坏死区。结论：对兔VX2肝移植瘤而言，超声检查筛查肿瘤生长情况，磁共振可以从分子水平上评价药物疗效，为下一步碘油联合壁虎活性单抗评价药效提供一定的依据。
目的：建立兔VX2肝移植瘤模型，對其影像學錶現進行評價，為下一步聯閤壁虎活性單體評價治療效果提供一定的參攷。方法：20隻兔新西蘭大白兔在無菌條件下接種VX2瘤組織塊，建立VX2肝移植瘤模型，2週後行超聲、3．0T磁共振，評價其影像錶現。結果：成瘤率為90％。超聲錶現為略高迴聲糰塊，沒有包膜，其內可見彊迴聲。TIWI錶現為低信號，T2WI錶現為高信號，增彊掃描後明顯彊化，內部有不彊化的壞死區。結論：對兔VX2肝移植瘤而言，超聲檢查篩查腫瘤生長情況，磁共振可以從分子水平上評價藥物療效，為下一步碘油聯閤壁虎活性單抗評價藥效提供一定的依據。
목적：건립토VX2간이식류모형，대기영상학표현진행평개，위하일보연합벽호활성단체평개치료효과제공일정적삼고。방법：20지토신서란대백토재무균조건하접충VX2류조직괴，건립VX2간이식류모형，2주후행초성、3．0T자공진，평개기영상표현。결과：성류솔위90％。초성표현위략고회성단괴，몰유포막，기내가견강회성。TIWI표현위저신호，T2WI표현위고신호，증강소묘후명현강화，내부유불강화적배사구。결론：대토VX2간이식류이언，초성검사사사종류생장정황，자공진가이종분자수평상평개약물료효，위하일보전유연합벽호활성단항평개약효제공일정적의거。
Objective:To establish liver transplantation tumor model of rabbits and evaluate the imaging features.Method:VX2 tumor pieces were implanted into the liver of 10 white New Zealand rabbits to establish VX2 Liver transplantation tumor model.18 days after transplantation,ultrasound,3.0T magnetic resonance imaging(MRI)were performed to evaluate the ima-ging features.Observe the pathological manifestation after examinations.Results:The successful rate of original neoplasia was 90%.The tumors were demonstrated as a lit le higher echo compa-nied with dark circle and high echo in the internal.The tumors were demonstrated as homogeneously hypointense in T1WI ,lightly hyperintense in T2WI and hyperintense in DWI.The tumors were demonstrated as the enhanced edge ,non enhancement zone clear center in DCE-MRI.MRI can evaluate the changes of the tumors from monecular.Lay a solid foundation of Intervention-al therapy combining with gecko active monomer for the next step.
