CAJ | 학술논문

采用常规皮内变态反应(TST方法)对唐山、秦皇岛、沧州和石家庄四个市共计2204头奶牛进行牛结核病检测，采用IFN-γ试验方法对PPD检测结果为阳性、可疑的牛以及部分阴性牛进行复检。将IFN-γ试验与TST检测结果相比较，其敏感性为78.26%，特异性为89.09%，符合率为84.33%。研究表明单独使用PPD皮内变态反应方法在牛结核病的诊断方面存在特异性差的缺点，用IFN-γ试验对TST试验阳性和可疑牛进行复检可以提高特异性，避免造成假阳性牛的误杀；该方法在临床上适合推广应用。
채용상규피내변태반응(TST방법)대당산、진황도、창주화석가장사개시공계2204두내우진행우결핵병검측，채용IFN-γ시험방법대PPD검측결과위양성、가의적우이급부분음성우진행복검。장IFN-γ시험여TST검측결과상비교，기민감성위78.26%，특이성위89.09%，부합솔위84.33%。연구표명단독사용PPD피내변태반응방법재우결핵병적진단방면존재특이성차적결점，용IFN-γ시험대TST시험양성화가의우진행복검가이제고특이성，피면조성가양성우적오살；해방법재림상상괄합추엄응용。
A total of 2 204 cows from Tangshan, Qin Huangdao, Cangzhou and Shi Jiazhuang were checked for bovine tuberculosis with the method of tuberculin skin test (TST), of which the positive, doubtful and some nega-tive results were rechecked byγ-interferon assay. The results ofγ-interferon assay which has a sensitivity of 78.26%and a specificity of 84.33%were compared to those of TST. According to that, the consistency rate of the two methods reached 84.33%. The study showed thatγ-interferon assay, which could improve the specificity and therefore avoid false culling, was suited for widespread clinical use.