CAJ | 학술논문

目的：观察输血剂量大小对门脉高压上消化道大出血治疗效果影响。方法85例患者随机分为等量输血组42例，1/2量输血组43例，在降低门脉压力药物的基础上等量输血组输注与估计失血量相当的悬浮红细胞，1/2量输血组则给予输注估计出血量的半量悬浮红细胞以补充血容量和纠正休克。结果1/2量输血组显效率37.2%，有效率53.5%；等量输血组显效率23.8%，有效率40.5%。2组有显著性差异（P<0.05）；2组输悬浮红细胞分别为212U和418U，有显著性差异（P<0.01）。结论针对门脉高压上消化道大出血输血补充血容量以不超过出血量1/2为宜，以免增加门静脉血流量，引起门脉高压持续不降，导致出血不止或再出血。
목적：관찰수혈제량대소대문맥고압상소화도대출혈치료효과영향。방법85례환자수궤분위등량수혈조42례，1/2량수혈조43례，재강저문맥압력약물적기출상등량수혈조수주여고계실혈량상당적현부홍세포，1/2량수혈조칙급여수주고계출혈량적반량현부홍세포이보충혈용량화규정휴극。결과1/2량수혈조현효솔37.2%，유효솔53.5%；등량수혈조현효솔23.8%，유효솔40.5%。2조유현저성차이（P<0.05）；2조수현부홍세포분별위212U화418U，유현저성차이（P<0.01）。결론침대문맥고압상소화도대출혈수혈보충혈용량이불초과출혈량1/2위의，이면증가문정맥혈류량，인기문맥고압지속불강，도치출혈불지혹재출혈。
Objective to observe the effect of blood transfusion volume on treatment efficacy in massive upper gastrointestinal hemorrhage patients with portal hypertension. Methods 85 massive upper gastrointestinal hemorrhage patients with portal hypertension were randomly divided into equal volume transfusion group( 42 cases) and half volume transfusion group ( 43 cases). in two groups, the red blood cell transfusion volume was equal and half of the blood loss volume respectively. Results the total red blood cell transfusion volume are 418 and 212 units in equal volume transfusion group and half volume transfusion group, respectively. the significant efficiency rate and efficiency rate in equal volume transfusion was 23.8%and 40.5% respectively. in half volume transfusion group, the significant efficiency rate and efficiency rate was 37.2% and 53.5%respectively. There was signiifcant difference of the signiifcant efifciency rate and efifciency rate between two groups. Conclusions the total blood transfusion volume in massive upper gastrointestinal hemorrhage patients with portal hypertension should not exceed half of the blood loss volume in order to avoid increasing the portal vein flow and pressure, so prevent rebleeding.