CAJ | 학술논문

目的：探讨阿奇霉素联合盐酸氨溴索治疗小儿哮喘的临床疗效。方法选取我院收治的84例哮喘患儿作为研究对象，使用随机数字表法分为治疗组和对照组，每组42例，对照组患儿常规应用阿奇霉素，治疗组在对照组基础上加用盐酸氨溴索，比较两组患儿的临床疗效。结果治疗组的显效率、总有效率均显著高于对照组，（P＜0.05），差异均具有统计学意义；治疗组的住院时间、体征及症状消失时间均明显比对照组更短，（P＜0.05）；对照组的不良反应发生率为7.1%，治疗组为9.5%，组间比较统计学无差异（P＞0.05）。结论临床治疗小儿哮喘，联合应用盐酸氨溴索和阿奇霉素可迅速缓解临床症状，其临床疗效确切，并且不会增加不良反应，值得推广应用。
목적：탐토아기매소연합염산안추색치료소인효천적림상료효。방법선취아원수치적84례효천환인작위연구대상，사용수궤수자표법분위치료조화대조조，매조42례，대조조환인상규응용아기매소，치료조재대조조기출상가용염산안추색，비교량조환인적림상료효。결과치료조적현효솔、총유효솔균현저고우대조조，（P＜0.05），차이균구유통계학의의；치료조적주원시간、체정급증상소실시간균명현비대조조경단，（P＜0.05）；대조조적불량반응발생솔위7.1%，치료조위9.5%，조간비교통계학무차이（P＞0.05）。결론림상치료소인효천，연합응용염산안추색화아기매소가신속완해림상증상，기림상료효학절，병차불회증가불량반응，치득추엄응용。
Objective To study the azithromycin ammonia bromine joint hydrochloric acid in the clinical curative effect of treatment of infantile asthma. Methods Select our hospital 84 cases of children with asthma as the research object, using a random number table method is divided into the treatment group and control group, 42 cases in each group, control group with routine application of azithromycin, the treatment group in the control group with hydrochloric acid based on ammonia bromine, compare the clinical curative effect of two groups of children. Results The signiifcant efifciency and total effective rate in treatment group were signiifcantly higher than that of control group, P<0.05, differences were statistically signiifcant;Treatment group hospitalization time, signs and symptoms disappear time were signiifcantly shorter than the control group, (P<0.05);The incidence of adverse reactions was 7.1%in the control group, treatment group was 9.5%, the comparison between groups there was no signiifcant difference (P>0.05). Conclusion The clinical treatment of pediatric asthma, ammonia bromine joint application of hydrochloric acid and azithromycin can rapidly relieve the clinical symptoms, the clinical curative effect, and will not increase adverse reactions, is worthy of popularization and application.