CAJ | 학술논문

2型糖尿病以胰岛素抵抗为病理基础。虽然膳食、生活方式等环境因素仍被认为是糖尿病的发病中的重要决定因素，但是糖尿病具有明显的家族遗传学基础，而线粒体基因组某些位点的点突变、缺失突变和重复突变均被证明与糖尿病发生密切相关。
2형당뇨병이이도소저항위병리기출。수연선식、생활방식등배경인소잉피인위시당뇨병적발병중적중요결정인소，단시당뇨병구유명현적가족유전학기출，이선립체기인조모사위점적점돌변、결실돌변화중복돌변균피증명여당뇨병발생밀절상관。
Type 2 diabetes is on the pathological basis of insulin resistance .Environmental factors such as diet , lifestyle, though, is still considered an important determinant of the onset of diabetes .However, diabetes have obvious family genetic basis , and some loci point mutation , deletion and repeat mutations of mitochondrial genome are proved to be closely associated with diabetes .