CAJ | 학술논문

目的：探讨类风湿性关节炎（ RA）合并冠心病患者临床血脂水平及发病关系相关性。方法将58例RA患者分为单纯RA组（32例）和RA合并冠心病组（26例），分别检测两组血脂水平，包括总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白（LDL－C）和高密度脂蛋白（HDL－C）。结果 RA合并冠心病组LDL－C水平高于单纯RA组，HDL－C水平低于单纯RA组，均有统计学差异（P＜0．05），两组TC、TG比较无统计学差异（P＞0．05）。结论 RA合并冠心病组较单纯RA患者存在更加明显高LDL－C血症及低HDL－C血症，提示可能为RA导致冠心病的重要原因，需要积极有效干预。
목적：탐토류풍습성관절염（ RA）합병관심병환자림상혈지수평급발병관계상관성。방법장58례RA환자분위단순RA조（32례）화RA합병관심병조（26례），분별검측량조혈지수평，포괄총담고순（TC）、감유삼지（TG）、저밀도지단백（LDL－C）화고밀도지단백（HDL－C）。결과 RA합병관심병조LDL－C수평고우단순RA조，HDL－C수평저우단순RA조，균유통계학차이（P＜0．05），량조TC、TG비교무통계학차이（P＞0．05）。결론 RA합병관심병조교단순RA환자존재경가명현고LDL－C혈증급저HDL－C혈증，제시가능위RA도치관심병적중요원인，수요적겁유효간예。
Objectives To explore blood fat level and characteristics analysis of rheumatoid arthritis ( RA) with coronary heart disease(CHD).Methods A total of 58 RA were subdivided as RA only group (n=32) and RA combined with CHD group (n=26).Blood fat level including TC,TG,LDL-C and HDL-C of two groups was detected.Results Compared with the RA only group, the level of LDL-C was higher ,while the level of HDL-C was lower in the RA combined with CHD group ( P<0.05) .But TC and TG were no statistical differences (P>0.05).Conclusions High LDL-C and low HDL-C is more prevalent in RA with CHD pa-tients which may be an important reason to CHD and need positive and effective intervention .