中国循环杂志
中國循環雜誌
중국순배잡지
CHINESE CIRCULATION JOURNAL
2015年
1期
6-8
,共3页
类风湿性关节炎%冠心病%心肌梗死%红细胞沉降率
類風濕性關節炎%冠心病%心肌梗死%紅細胞沉降率
류풍습성관절염%관심병%심기경사%홍세포침강솔
Rheumatoid arthritis%Coronary artery disease%Myocardial infarction%Erythrocyte Sedimentation Rate
目的：探讨类风湿性关节炎合并冠心病患者的红细胞沉降率与发生心肌梗死的关系。<br> 方法：连续入选类风湿性关节炎合并冠心病患者106例，男性46例，女性60例，其中发生过心肌梗死患者46例（心肌梗死组），未发生过心肌梗死患者60例（非心肌梗死组）。比较两组患者的基线资料。用logistic回归的方法探究类风湿性关节炎合并冠心病患者发生心肌梗死的相关危险因素。<br> 结果：胆固醇水平心肌梗死组明显低于非心肌梗死组（P<0.05）。炎症活动性指标红细胞沉降率，高敏C反应蛋白及C反应蛋白水平心肌梗死组均明显高于非心肌梗死组（P<0.05）。两组其它基线资料相比均无统计学差异（P>0.05）。多元logistic回归模型得出该人群发生心肌梗死的相关危险因素为红细胞沉降率（风险比：1.024；95%可信区间：1.007~1.043；P=0.007）。<br> 结论：类风湿性关节炎合并冠心病患者红细胞沉降率与心肌梗死的发生有独立关联。
目的：探討類風濕性關節炎閤併冠心病患者的紅細胞沉降率與髮生心肌梗死的關繫。<br> 方法：連續入選類風濕性關節炎閤併冠心病患者106例，男性46例，女性60例，其中髮生過心肌梗死患者46例（心肌梗死組），未髮生過心肌梗死患者60例（非心肌梗死組）。比較兩組患者的基線資料。用logistic迴歸的方法探究類風濕性關節炎閤併冠心病患者髮生心肌梗死的相關危險因素。<br> 結果：膽固醇水平心肌梗死組明顯低于非心肌梗死組（P<0.05）。炎癥活動性指標紅細胞沉降率，高敏C反應蛋白及C反應蛋白水平心肌梗死組均明顯高于非心肌梗死組（P<0.05）。兩組其它基線資料相比均無統計學差異（P>0.05）。多元logistic迴歸模型得齣該人群髮生心肌梗死的相關危險因素為紅細胞沉降率（風險比：1.024；95%可信區間：1.007~1.043；P=0.007）。<br> 結論：類風濕性關節炎閤併冠心病患者紅細胞沉降率與心肌梗死的髮生有獨立關聯。
목적：탐토류풍습성관절염합병관심병환자적홍세포침강솔여발생심기경사적관계。<br> 방법：련속입선류풍습성관절염합병관심병환자106례，남성46례，녀성60례，기중발생과심기경사환자46례（심기경사조），미발생과심기경사환자60례（비심기경사조）。비교량조환자적기선자료。용logistic회귀적방법탐구류풍습성관절염합병관심병환자발생심기경사적상관위험인소。<br> 결과：담고순수평심기경사조명현저우비심기경사조（P<0.05）。염증활동성지표홍세포침강솔，고민C반응단백급C반응단백수평심기경사조균명현고우비심기경사조（P<0.05）。량조기타기선자료상비균무통계학차이（P>0.05）。다원logistic회귀모형득출해인군발생심기경사적상관위험인소위홍세포침강솔（풍험비：1.024；95%가신구간：1.007~1.043；P=0.007）。<br> 결론：류풍습성관절염합병관심병환자홍세포침강솔여심기경사적발생유독립관련。
Objective: To explore the relationship between erythrocyte sedimentation rate (ESR) and myocardial infarction (MI) occurrence in patients with rheumatoid arthritis (RA) combining coronary artery disease (CAD). <br> Methods: A total of 106 consecutive patients with RA combining CAD were studied. There were 46 male and 60 female patients and divided into 2 groups:RA with MI group, n=46 and RA without MI group, n=60. The base line condition was compared between 2 groups, and multivariate regression analysis was conducted to explore the risk factors for MI occurrence in relevant patients. <br> Results: Compared with RA without MI group, RA with MI group had the lower level of cholesterol and higher levels of inlfammatory indexes of ESR, high sensitivity C-reactive protein (hs-CRP) and CRP, P<0.05. The base line condition was similar between 2 group, P>0.05. Multivariate regression analysis indicated that ESR was the independent risk factor of MI occurrence, OR=1.024, 95%CI 1.024 (1.007-1.043), P=0.007. <br> Conclusion: ESR was independently related to MI occurrence in patients with RA combining CAD.
