CAJ | 학술논문

目的：探讨慢性右心衰竭（右心衰）与慢性全心衰竭（全心衰）的通气功能的差异。 　　方法：102例临床稳定的慢性心力衰竭（心衰）患者入选该研究，根据心衰情况分为全心衰者（41例），右心衰者（61例）。所有患者均测定静息状态下通气功能，心肺运动试验（CPX）测定运动状态下通气功能。 　　结果：静息状态下，全心衰者及右心衰者通气功能无差异。运动状态下，右心衰者峰值分钟通气量（peak VE）明显低于全心衰者（P<0.05），而无氧阈及峰值分钟通气量与二氧化碳（CO2）生成量比值（VE/VCO2），峰值死腔通气量与潮气量比值（peak VD/VT）高于全心衰者（P<0.05），差异均有统计学意义。 　　结论：静息状态，全心衰者与右心衰者通气功能无差异。运动状态下，右心衰者通气功能及通气效率降低，其原因在于严重的通气血流比（V/Q）异常。
목적：탐토만성우심쇠갈（우심쇠）여만성전심쇠갈（전심쇠）적통기공능적차이。 　　방법：102례림상은정적만성심력쇠갈（심쇠）환자입선해연구，근거심쇠정황분위전심쇠자（41례），우심쇠자（61례）。소유환자균측정정식상태하통기공능，심폐운동시험（CPX）측정운동상태하통기공능。 　　결과：정식상태하，전심쇠자급우심쇠자통기공능무차이。운동상태하，우심쇠자봉치분종통기량（peak VE）명현저우전심쇠자（P<0.05），이무양역급봉치분종통기량여이양화탄（CO2）생성량비치（VE/VCO2），봉치사강통기량여조기량비치（peak VD/VT）고우전심쇠자（P<0.05），차이균유통계학의의。 　　결론：정식상태，전심쇠자여우심쇠자통기공능무차이。운동상태하，우심쇠자통기공능급통기효솔강저，기원인재우엄중적통기혈류비（V/Q）이상。
Objective:To study the differences of ventilation function in patients between chronic right heart failure secondary to pulmonary arterial hypertension and chronic whole heart failure secondary to left heart diseases. Methods:A total of 102 patients with clinical stable chronic heart failure (CHF) were studied. The patients were divided into 2 groups:Whole heart failure (WHF) group, n=41 and Right heart failure (RHF) group, n=61. The ventilation function test at rest and cardiopulmonary exercise test (CPX) were conducted and compared between 2 groups. Results: The rest ventilation function was similar between 2 groups. For CPX examination, compared with WHF group, RHF group had the lower peak minute ventilation (VE), higher anaerobic threshold and peak minute ventilation/CO2 production (VE/VCO2), higher peak dead space volume/tidal volume (VD/VT), all P<0.05. Conclusion:At exercise condition, RHF patients had decreased ventilation function and ventilation index due to severe abnormality of ventilation/perfusion (V/Q).