中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2015年
6期
41-42
,共2页
热休克蛋白70%急性心肌梗死%左室重构
熱休剋蛋白70%急性心肌梗死%左室重構
열휴극단백70%급성심기경사%좌실중구
Heat shock protein 70%Acute myocardial infarction%Left ventricular remodeling
目的：探讨热休克蛋白70(HSP70)与急性心肌梗死(AMI)后心室重构的相关性。方法78例急性心肌梗死患者,根据6个月后左室舒张末期容积指数是否较基线值增加20%将其分为左室重构(LVR)组和非左室重构(NLVR)组。入院后第2天清晨空腹测静脉血中的HSP70,发病第3天和6个月分别行心脏超声心动图测定左室舒张末期容积(LVEDV)。结果 LVR组中HSP70水平高于NLVR组,差异具有统计学意义(P<0.05), LVR组中HSP70水平与LVEDV呈正相关(P<0.05)。结论 AMI后HSP70的表达参与了左室重构的发生,对左室重构有一定的预测价值。
目的：探討熱休剋蛋白70(HSP70)與急性心肌梗死(AMI)後心室重構的相關性。方法78例急性心肌梗死患者,根據6箇月後左室舒張末期容積指數是否較基線值增加20%將其分為左室重構(LVR)組和非左室重構(NLVR)組。入院後第2天清晨空腹測靜脈血中的HSP70,髮病第3天和6箇月分彆行心髒超聲心動圖測定左室舒張末期容積(LVEDV)。結果 LVR組中HSP70水平高于NLVR組,差異具有統計學意義(P<0.05), LVR組中HSP70水平與LVEDV呈正相關(P<0.05)。結論 AMI後HSP70的錶達參與瞭左室重構的髮生,對左室重構有一定的預測價值。
목적：탐토열휴극단백70(HSP70)여급성심기경사(AMI)후심실중구적상관성。방법78례급성심기경사환자,근거6개월후좌실서장말기용적지수시부교기선치증가20%장기분위좌실중구(LVR)조화비좌실중구(NLVR)조。입원후제2천청신공복측정맥혈중적HSP70,발병제3천화6개월분별행심장초성심동도측정좌실서장말기용적(LVEDV)。결과 LVR조중HSP70수평고우NLVR조,차이구유통계학의의(P<0.05), LVR조중HSP70수평여LVEDV정정상관(P<0.05)。결론 AMI후HSP70적표체삼여료좌실중구적발생,대좌실중구유일정적예측개치。
Objective To investigate the correlation between heat shock protein 70 (HSP70) and ventricular remodeling after acute myocardial infarction (AMI). Methods A total of 78 patients with AMI were divided into left ventricular remodeling (LVR) group and non left ventricular remodeling (NLVR) group, according to whether their LVEDV was increased 20%more than basic level after 6 months. Their levels of HSP70 were detected in venous blood in the second morning of admission. Ultrasonic cardiography was applied for detection of left ventricular end diastolic volume (LVEDV) on the third day and the sixth month of disease. Results The LVR group had higher HSP70 level than the NLVR group, and the difference had statistical significance (P<0.05). HSP70 level was positively correlated with LVEDV in the LVR group (P<0.05). Conclusion Expression of HSP70 is involved in the occurrence of LVR after AMI, and it has a certain value in prediction for LVR.
