大家健康(中旬版)
大傢健康(中旬版)
대가건강(중순판)
GOOD HEALTH FOR ALL
2015年
1期
8-9
,共2页
洛伐他汀%脂肪肝%肝功能
洛伐他汀%脂肪肝%肝功能
락벌타정%지방간%간공능
lovastatin%steatohepatitis%liver function
目的:观察洛伐他汀对非酒精性脂肪性肝炎治疗的疗效,探讨洛伐他汀降血脂改善肝脏脂肪变性与炎性程度的作用。方法:90例患者随机分为洛伐他汀组和对照组两组,每组45例,洛伐他汀组在常规保肝治疗基础上采用洛伐他汀治疗,对照组只进行常规保肝治疗,分别观察疗效。结果:洛伐他汀组与对照组疗程结束后,血脂水平及肝功能情况均有显著改变(P <0.05);洛伐他汀组治疗后显效36例,有效7例,无效2例;对照组显效28例,有效10例,无效7例;洛伐他汀组降血脂改善肝功能的效果也明显好于对照组,两组疗效差异有统计学意义(P <0.05)。结论:洛伐他汀应用于治疗脂肪肝效果明显,不良反应小。
目的:觀察洛伐他汀對非酒精性脂肪性肝炎治療的療效,探討洛伐他汀降血脂改善肝髒脂肪變性與炎性程度的作用。方法:90例患者隨機分為洛伐他汀組和對照組兩組,每組45例,洛伐他汀組在常規保肝治療基礎上採用洛伐他汀治療,對照組隻進行常規保肝治療,分彆觀察療效。結果:洛伐他汀組與對照組療程結束後,血脂水平及肝功能情況均有顯著改變(P <0.05);洛伐他汀組治療後顯效36例,有效7例,無效2例;對照組顯效28例,有效10例,無效7例;洛伐他汀組降血脂改善肝功能的效果也明顯好于對照組,兩組療效差異有統計學意義(P <0.05)。結論:洛伐他汀應用于治療脂肪肝效果明顯,不良反應小。
목적:관찰락벌타정대비주정성지방성간염치료적료효,탐토락벌타정강혈지개선간장지방변성여염성정도적작용。방법:90례환자수궤분위락벌타정조화대조조량조,매조45례,락벌타정조재상규보간치료기출상채용락벌타정치료,대조조지진행상규보간치료,분별관찰료효。결과:락벌타정조여대조조료정결속후,혈지수평급간공능정황균유현저개변(P <0.05);락벌타정조치료후현효36례,유효7례,무효2례;대조조현효28례,유효10례,무효7례;락벌타정조강혈지개선간공능적효과야명현호우대조조,량조료효차이유통계학의의(P <0.05)。결론:락벌타정응용우치료지방간효과명현,불량반응소。
Objective:To observe the effect of lovastatin on the treatment of non -alcoholic steatohepatitis.Methods:90 patients with fatty liver were di-vided randomly into two groups of the lovastatin group and the control group(45 cases/group).Lovastatin group was treated with lovastatin on the basis of routine therapy,while the control group was treated only routine therapy to improve liver function.Effects of treatment were observed respectively.Results:After treat-ment,serum lipid levels and liver function was significantly improved in both the lovastatin group and the control group (P <0.05).In the lovastatin group,36 cases had markedly improved after treatment,while in hte control group,only 28 cases had markedly improved.The effect of treatment in the lovastatin group was obviously better than that in the control group (P <0.05).Conclusion:Lovastatin is safe and effective in the treatment of fatty liver.