CAJ | 학술논문

目的：探讨超声造影在伴有钙化的甲状腺结节诊断中的临床价值。方法对73例甲状腺良性结节和53例甲状腺恶性结节患者分别进二维超声和超声造影检查，比较良恶性结节微钙化、弱增强及不均匀增强的构成比，并比较超声造影时良恶性结节始增时间、达峰时间和峰值强度。结果伴有钙化的甲状腺恶性结节微钙化、弱增强及不均匀增强的构成比均高于良性结节（ P ﹤0.05）；超声造影恶性结节峰值强度低于良性结节（ P ﹤0.05），良恶性结节始增时间、达峰时间差异无统计学意义（ P ﹥0.05）；超声造影对伴有钙化甲状腺结节良恶性诊断的敏感度、特异度、阳性预测值及阴性预测值均高于二维超声检查（ P ﹤0.05）。结论超声造影可敏感、动态地观察甲状腺结节的增强特点，对伴有钙化的甲状腺结节的诊断具有较高的临床价值。
목적：탐토초성조영재반유개화적갑상선결절진단중적림상개치。방법대73례갑상선량성결절화53례갑상선악성결절환자분별진이유초성화초성조영검사，비교량악성결절미개화、약증강급불균균증강적구성비，병비교초성조영시량악성결절시증시간、체봉시간화봉치강도。결과반유개화적갑상선악성결절미개화、약증강급불균균증강적구성비균고우량성결절（ P ﹤0.05）；초성조영악성결절봉치강도저우량성결절（ P ﹤0.05），량악성결절시증시간、체봉시간차이무통계학의의（ P ﹥0.05）；초성조영대반유개화갑상선결절량악성진단적민감도、특이도、양성예측치급음성예측치균고우이유초성검사（ P ﹤0.05）。결론초성조영가민감、동태지관찰갑상선결절적증강특점，대반유개화적갑상선결절적진단구유교고적림상개치。
Objective To explore the clinical significance of contrast - enhanced ultrasound(CEUS)in diagnosis of calcified thyroid nodules. Methods Seventy three patients with benign thyroid nodules and 53 patients with malignant thyroid nodules were examined with two -dimensional ultrasound and CEUS respectively,and the constituent ratio of microcalcification,weak enhancement and inhomogeneous enhancement of benign and malignant nodules were compared,and time for beginning enhancement,duration to peak and peak intensity of benign and malignant nodules examined by CEUS were compared,and diagnostic value of CEUS and two - dimensional ultrasound in diagnosis of calcified thyroid nod-ules had been compared. Results The constituent ratio of microcalcification,weak enhancement and inhomogeneous enhancement of malignant nodules were higher than those of benign nodules( P ﹤ 0. 05). The peak strength of malignant nodules under CEUS was lower than that of benign nodules( P ﹤ 0. 05),there was no statistically significant difference in enhancement beginning time,time to peak of benign and malignant nodules ( P ﹥ 0. 05). The sensitivity,specificity,positive predictive value and negative predictive value of CEUS in diagnosis of benign and malignant calcified thyroid nodules were higher than those of two - dimensional echocardiography( P ﹤ 0. 05). Conclusion CEUS has sensitive and dynam-ic characteristics in observation of thyroid nodules and it has a high clinical value in diagnosis of calcified thyroid nodules.