CAJ | 학술논문

目的：采用化学位移 MRI 研究初诊2型糖尿病患者的胰腺脂肪含量及分布特点，并探讨胰腺与肝脏脂肪含量的相关性。方法征集初诊的2型糖尿病患者70例，采用化学位移双回波 MRI 技术分别测量胰腺头部、体部、尾部及肝脏的脂肪含量，比较胰腺头部、体部、尾部的脂肪含量差异，分析胰腺脂肪含量与肝脏脂肪含量的相关性。结果本组患者胰腺头部、体部、尾部的脂肪分数分别为5.59％±4.70％、4.80％±3.75％、4.88％±3.86％，三个区域的脂肪含量没有统计学差异（ F =1.761，P ﹥0.05）。胰腺的平均脂肪分数为5.15％±3.75％，肝脏为9.88％±3.19％，胰腺的脂肪含量与肝脏的脂肪含量没有相关性（ r =0.053，P ﹥0.05）。结论初诊的2型糖尿病患者胰腺头、体、尾部的脂肪含量较为一致，胰腺的脂肪含量与肝脏的脂肪含量不相关。
목적：채용화학위이 MRI 연구초진2형당뇨병환자적이선지방함량급분포특점，병탐토이선여간장지방함량적상관성。방법정집초진적2형당뇨병환자70례，채용화학위이쌍회파 MRI 기술분별측량이선두부、체부、미부급간장적지방함량，비교이선두부、체부、미부적지방함량차이，분석이선지방함량여간장지방함량적상관성。결과본조환자이선두부、체부、미부적지방분수분별위5.59％±4.70％、4.80％±3.75％、4.88％±3.86％，삼개구역적지방함량몰유통계학차이（ F =1.761，P ﹥0.05）。이선적평균지방분수위5.15％±3.75％，간장위9.88％±3.19％，이선적지방함량여간장적지방함량몰유상관성（ r =0.053，P ﹥0.05）。결론초진적2형당뇨병환자이선두、체、미부적지방함량교위일치，이선적지방함량여간장적지방함량불상관。
Objective To investigate the fat content and distribution of the pancreas,and to explore its relation with hepatic fat content by chemical shift MRI in patients with newly - diagnosed type 2 diabetes. Methods 70 patients with newly - diagnosed type 2 diabetes were recrui-ted in this study. Fat content in the pancreatic head,body,tail and the liver was respectively measured with the technique of double - echo chemi-cal shift gradient - echo magnetic resonance imaging. The fat fraction in the pancreatic head,body and tail was compared. Its relation with hepatic fat fraction was analyzed. Results The fat fraction in the pancreatic head,body and tail was 5. 59% ± 4. 70% ,4. 80% ± 3. 75% and 4. 88% ± 3. 86% ,respectively,and there was no statistical difference among them( F = 1. 761,P ﹥ 0. 05). The mean value of fat fraction in the pancreas and the liver was 5. 15% ± 3. 75% and 9. 88% ± 3. 19% ,respectively. They were not correlated each other( r = 0. 053,P ﹥ 0. 05). Conclu-sion Fat content in the head,body and tail of the pancreas was basically even. And the pancreatic and hepatic fat content was not correlated in patients with newly - diagnosed type 2 diabetes.