中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
4期
35-36,38
,共3页
罗开开%黄永光%胡海波%白光
囉開開%黃永光%鬍海波%白光
라개개%황영광%호해파%백광
结肠癌并肠梗阻%丙氨酰-谷氨酰胺%全胃肠外营养%免疫功能
結腸癌併腸梗阻%丙氨酰-穀氨酰胺%全胃腸外營養%免疫功能
결장암병장경조%병안선-곡안선알%전위장외영양%면역공능
Cancer complicated with intestinal obstruction%Alanyl-glutamine%Total parenteral nutrition%Immunity
目的：探讨丙氨酰-谷氨酰胺双肽强化肠外营养在结肠癌合并肠梗阻治疗中的临床价值。方法：2012年2月-2014年3月收治择期行手术治疗的结肠癌合并肠梗阻患者46例，按照随机数字法分为观察组和对照组各23例，观察组分别于术前和术后接受丙氨酰-谷氨酰胺双肽强化肠外营养干预，对照组仅接受标准肠外营养干预，并对两组患者手术前后的营养学指标、术后恢复和免疫学指标进行评价。结果：营养学指标方面：术后8 d，观察组在 ALB、PAB、TF 和氮平衡方面均显著高于对照组(P＜0.05)；术后恢复方面：观察组在手术前、后体重变化值及术后排气、住院时间均显著少于对照组(P＜0.05)；免疫指标方面：术后8 d，观察组在IgA、IgG、IgM和淋巴细胞计数均高于对照组(P＜0.05)。结论：丙氨酰-谷氨酰胺双肽强化肠外营养在结肠癌合并肠梗阻治疗中应用效果显著，能有效改善患者营养学指标，提高患者免疫功能，加快恢复速度，且安全，值得临床推广。
目的：探討丙氨酰-穀氨酰胺雙肽彊化腸外營養在結腸癌閤併腸梗阻治療中的臨床價值。方法：2012年2月-2014年3月收治擇期行手術治療的結腸癌閤併腸梗阻患者46例，按照隨機數字法分為觀察組和對照組各23例，觀察組分彆于術前和術後接受丙氨酰-穀氨酰胺雙肽彊化腸外營養榦預，對照組僅接受標準腸外營養榦預，併對兩組患者手術前後的營養學指標、術後恢複和免疫學指標進行評價。結果：營養學指標方麵：術後8 d，觀察組在 ALB、PAB、TF 和氮平衡方麵均顯著高于對照組(P＜0.05)；術後恢複方麵：觀察組在手術前、後體重變化值及術後排氣、住院時間均顯著少于對照組(P＜0.05)；免疫指標方麵：術後8 d，觀察組在IgA、IgG、IgM和淋巴細胞計數均高于對照組(P＜0.05)。結論：丙氨酰-穀氨酰胺雙肽彊化腸外營養在結腸癌閤併腸梗阻治療中應用效果顯著，能有效改善患者營養學指標，提高患者免疫功能，加快恢複速度，且安全，值得臨床推廣。
목적：탐토병안선-곡안선알쌍태강화장외영양재결장암합병장경조치료중적림상개치。방법：2012년2월-2014년3월수치택기행수술치료적결장암합병장경조환자46례，안조수궤수자법분위관찰조화대조조각23례，관찰조분별우술전화술후접수병안선-곡안선알쌍태강화장외영양간예，대조조부접수표준장외영양간예，병대량조환자수술전후적영양학지표、술후회복화면역학지표진행평개。결과：영양학지표방면：술후8 d，관찰조재 ALB、PAB、TF 화담평형방면균현저고우대조조(P＜0.05)；술후회복방면：관찰조재수술전、후체중변화치급술후배기、주원시간균현저소우대조조(P＜0.05)；면역지표방면：술후8 d，관찰조재IgA、IgG、IgM화림파세포계수균고우대조조(P＜0.05)。결론：병안선-곡안선알쌍태강화장외영양재결장암합병장경조치료중응용효과현저，능유효개선환자영양학지표，제고환자면역공능，가쾌회복속도，차안전，치득림상추엄。
Objective:To explore the clinical value of alanyl-glutamine enriched parenteral nutrition in the treatment of colon cancer complicated with intestinal obstruction.Methods:46 patients with colon cancer complicated with intestinal obstruction with elective operation were selected from February 2012 to March 2014.According to the random number method,they were divided into the observation group and the control group with 23 cases in each group.The observation group were given alanyl-glutamine enriched parenteral nutrition intervention.The control group were given standard intestinal parenteral nutrition intervention.We compared the nutritional index,postoperative recovery and immunology index before and after operation of the two groups.Results:Nutrition indicators:8 days after the operation,in the observation group,ALB,PAB,TF and nitrogen balance were significantly higher than those in control group (P<0.05);the postoperative recovery:in the observation group,the body weight changes before and after surgery and postoperative exhaust and postoperative hospitalization time were significantly less than those of the control group(P<0.05);immune indicators:8 days after the operation,in the observation group,IgA,IgG,IgM and lymphocyte count were higher than those of the control group(P<0.05).Conclusion:The clinical effect of alanyl-glutamine enriched parenteral nutrition in the treatment of colon cancer complicated with intestinal obstruction is significant.It can improve the nutritional index effectively, improve the immunity function of patients,and accelerate the speed of recovery.It is safe and worth the clinical promotion.
