中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
4期
109-110
,共2页
重症肺炎%前降钙素%预后
重癥肺炎%前降鈣素%預後
중증폐염%전강개소%예후
Severe pneumonia%Procalcitonin%Prognosis
目的：分析重症肺炎患者前降钙素(PCT)的变化，探讨其意义及对预后的影响。方法：收治重症肺炎患者47例，于入院后第1、3、5天及离开ICU前测定PCT值，根据预后将患者分为生存组和死亡组，比较两组患者PCT值变化、急性生理和慢性健康评分(APACHE Ⅱ评分)、中心静脉血氧饱和度(ScvO2)。结果：死亡组第1天 PCT 值、APACHE II评分高于生存组，ScvO2低于生存组，但差异均无统计学意义(P＞0.05)，死亡组和生存组第3、5天及离开ICU前PCT值、APACHEⅡ评分高于生存组，ScvO2低于生存组，差异均有统计学意义(P＜0.05)，且死亡组PCT值呈进行性上升趋势，生存组呈下降趋势。结论：重症肺炎患者PCT水平与病情严重性有明显相关性，PCT水平对判断其病程发展、预后有一定价值。
目的：分析重癥肺炎患者前降鈣素(PCT)的變化，探討其意義及對預後的影響。方法：收治重癥肺炎患者47例，于入院後第1、3、5天及離開ICU前測定PCT值，根據預後將患者分為生存組和死亡組，比較兩組患者PCT值變化、急性生理和慢性健康評分(APACHE Ⅱ評分)、中心靜脈血氧飽和度(ScvO2)。結果：死亡組第1天 PCT 值、APACHE II評分高于生存組，ScvO2低于生存組，但差異均無統計學意義(P＞0.05)，死亡組和生存組第3、5天及離開ICU前PCT值、APACHEⅡ評分高于生存組，ScvO2低于生存組，差異均有統計學意義(P＜0.05)，且死亡組PCT值呈進行性上升趨勢，生存組呈下降趨勢。結論：重癥肺炎患者PCT水平與病情嚴重性有明顯相關性，PCT水平對判斷其病程髮展、預後有一定價值。
목적：분석중증폐염환자전강개소(PCT)적변화，탐토기의의급대예후적영향。방법：수치중증폐염환자47례，우입원후제1、3、5천급리개ICU전측정PCT치，근거예후장환자분위생존조화사망조，비교량조환자PCT치변화、급성생리화만성건강평분(APACHE Ⅱ평분)、중심정맥혈양포화도(ScvO2)。결과：사망조제1천 PCT 치、APACHE II평분고우생존조，ScvO2저우생존조，단차이균무통계학의의(P＞0.05)，사망조화생존조제3、5천급리개ICU전PCT치、APACHEⅡ평분고우생존조，ScvO2저우생존조，차이균유통계학의의(P＜0.05)，차사망조PCT치정진행성상승추세，생존조정하강추세。결론：중증폐염환자PCT수평여병정엄중성유명현상관성，PCT수평대판단기병정발전、예후유일정개치。
Objective:To analyze the procalcitonin(PCT) changes of patients with severe pneumonia,to explore its significance and influence on prognosis.Methods:47 patients with severe pneumonia were selected.The PCT value was measured at the first day,the third day,the fifth day after admission and before leaving ICU.According to prognosis,patients were divided into the survival group and the death group.We compared the changes of PCT value,acute physiology and chronic health score(APACHE score),central venous oxygen saturation(ScvO2) of the two groups.Results:In death group,PCT value,APACHE Ⅱ score at the third day were higher than the survival group,and ScvO2 was less than the survival group,with no significant difference(P>0.05).In the death group and the survival group,the value of PCT and APACHE Ⅱ score at the third day,the fifth day and before leaving ICU were higher than the survival group,and ScvO2 was less than the survival group;the difference was statistically significant(P<0.05).In death group,PCT value was of a rising trend,and the survival group was a downward trend.Conclusion:In patients with severe pneumonia,PCT levels had significant correlation with disease severity,and PCT level was helpful for predicting disease development and prognosis.
