CAJ | 학술논문

目的：探讨血液灌流联合血液透析救治重度急性中毒的临床疗效。方法选取60例重症急性中毒患者。按照随机数字表法平均分为对照组与试验组（n=30）。对照组给予常规治疗，试验组给予血液灌流联合血液透析治疗，比较2组患者的临床效果。结果试验组治愈例数（27例）显著多于对照组（19例），差异具有统计学意义（P<0.05）。2组患者治疗后试验组的生理指标[ BUN、CR、SGPT、DB、CK、LDH分别为（9.38±4.6）、（215.7±95.8）、（136.8±34.5）、（6.4±2.7）、（110.6±54.6）、（287.9±144.3）]均显著低于对照组[（14.7±7.3）、（359.7±101.4）、（137.8±34.9）、（12.7±4.1）、（308.5±114.6）、（484.6±144.7）]，2组差异具有统计学意义（P<0.05）。结论血液灌流联合血液透析治疗重症急性中毒的临床效果突出，能缩短住院时间，加快康复进程，值得推广。
목적：탐토혈액관류연합혈액투석구치중도급성중독적림상료효。방법선취60례중증급성중독환자。안조수궤수자표법평균분위대조조여시험조（n=30）。대조조급여상규치료，시험조급여혈액관류연합혈액투석치료，비교2조환자적림상효과。결과시험조치유례수（27례）현저다우대조조（19례），차이구유통계학의의（P<0.05）。2조환자치료후시험조적생리지표[ BUN、CR、SGPT、DB、CK、LDH분별위（9.38±4.6）、（215.7±95.8）、（136.8±34.5）、（6.4±2.7）、（110.6±54.6）、（287.9±144.3）]균현저저우대조조[（14.7±7.3）、（359.7±101.4）、（137.8±34.9）、（12.7±4.1）、（308.5±114.6）、（484.6±144.7）]，2조차이구유통계학의의（P<0.05）。결론혈액관류연합혈액투석치료중증급성중독적림상효과돌출，능축단주원시간，가쾌강복진정，치득추엄。
Objective To discuss the clincial efficacy of blood perfusion combined hemodialysis treatment for severe acute poisoning. Methods To select 60 patients with severe acute poisoning and divided into the control group and the experimental group according to the random number table method, 30 cases in each group. The control group was given conventional treatment, the experimental group was given blood perfusion combined hemodialysis treatment,to compare the clinical effect of two groups of patients. Results The patients of the experimenta group with cured cases (27 cases)were signiifcantly more than the control group (19 cases), it had statistically signiifcant difference (P<0.05).The experimental group with physiological indexes of BUN, CR, SGPT, DB, CK and LDH[(9.38±4.6)、(215.7±95.8)、(136.8±34.5)、(6.4±2.7)、(110.6±54.6)、(287.9±144.3)] were signiifcantly lower than the control group [(14.7±7.3)、(359.7±101.4)、(137.8±34.9)、(12.7±4.1)、(308.5±114.6)、(484.6±144.7)] after treatment, the difference had statistical signiifcance (P<0.05). Conclusion The clinical efifcacy of blood perfusion combined hemodialysis treatment of severe acute poisoning is obvious, it can shorten the length of hospital stay and speed up the recovery process,it is worth promoting.