中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2015年
2期
147-149
,共3页
无创机械通气%氧疗%急性肺损伤%呼吸窘迫综合征%系统评价
無創機械通氣%氧療%急性肺損傷%呼吸窘迫綜閤徵%繫統評價
무창궤계통기%양료%급성폐손상%호흡군박종합정%계통평개
Noninvasive mechanical ventilation%Oxygen therapy%Acute lung injury%Respiratory distress syndrome%System evaluation
目的：荟萃分析无创机械通气(NIV)在急性肺损伤及呼吸窘迫综合征患者中的应用效果。方法：系统检索Cochrane数据库、EMBASE、MEDLINE、Pubmed、Web of science、清华同方数据库、万方数据库、维普数据库，收集无创机械通气在急性损伤或呼吸窘迫综合征治疗效果方面的文献，参照Cochrane系统评价的方法对资料进行统计分析。结果：最终有5篇文献179例患者纳入研究。按随机效应模型合并分析后发现，NIV组气管插管率显著低于常规氧疗组(OR=0.17，95%CI：0.04~0.67，P=0.01)；但死亡率并未较常规氧疗组有所减少(OR=0.32，95%CI：0.09~1.071， P=0.06)。结论：与常规氧疗相比，无创机械通气可以显著减少急性肺损伤及急性呼吸窘迫综合征患者气管插管率，但不能减低患者死亡率。
目的：薈萃分析無創機械通氣(NIV)在急性肺損傷及呼吸窘迫綜閤徵患者中的應用效果。方法：繫統檢索Cochrane數據庫、EMBASE、MEDLINE、Pubmed、Web of science、清華同方數據庫、萬方數據庫、維普數據庫，收集無創機械通氣在急性損傷或呼吸窘迫綜閤徵治療效果方麵的文獻，參照Cochrane繫統評價的方法對資料進行統計分析。結果：最終有5篇文獻179例患者納入研究。按隨機效應模型閤併分析後髮現，NIV組氣管插管率顯著低于常規氧療組(OR=0.17，95%CI：0.04~0.67，P=0.01)；但死亡率併未較常規氧療組有所減少(OR=0.32，95%CI：0.09~1.071， P=0.06)。結論：與常規氧療相比，無創機械通氣可以顯著減少急性肺損傷及急性呼吸窘迫綜閤徵患者氣管插管率，但不能減低患者死亡率。
목적：회췌분석무창궤계통기(NIV)재급성폐손상급호흡군박종합정환자중적응용효과。방법：계통검색Cochrane수거고、EMBASE、MEDLINE、Pubmed、Web of science、청화동방수거고、만방수거고、유보수거고，수집무창궤계통기재급성손상혹호흡군박종합정치료효과방면적문헌，삼조Cochrane계통평개적방법대자료진행통계분석。결과：최종유5편문헌179례환자납입연구。안수궤효응모형합병분석후발현，NIV조기관삽관솔현저저우상규양료조(OR=0.17，95%CI：0.04~0.67，P=0.01)；단사망솔병미교상규양료조유소감소(OR=0.32，95%CI：0.09~1.071， P=0.06)。결론：여상규양료상비，무창궤계통기가이현저감소급성폐손상급급성호흡군박종합정환자기관삽관솔，단불능감저환자사망솔。
Objective:To make a meta-analysis of the application effect of noninvasive mechanical ventilation (NIV) in patients with acute lung injury and acute respiratory distress syndrome.Method:The literatures about the treatment effect of NIV in acute lung injury and acute respiratory distress syndrome in the Cochrane database,EMBASE,MEDLINE,Pubmed,Web of science,Tsinghua Tongfang database,Database,VIP database were selected systematically. The data with Meta method according to Cochrane system evaluation were statistically analyzed.Result:Five articles and 179 patients were included.Test of the analysis combined by random effects model showed that the endotracheal intubation rate of the NIV group was significantly lower than conventional oxygen therapy group(OR=0.17,95%CI:0.04-0.67,P=0.01),but the mortality rate did not decrease compared with the conventional oxygen therapy group(OR=0.32,95%CI:0.09-1.071,P=0.06).Conclusion:Compared with the conventional oxygen therapy group,NIV can significantly reduce the intubation rate of acute lung injury and acute respiratory distress syndrome,but can’t reduce mortality.
