CAJ | 학술논문

目的：研究同时运用阿托伐他汀以及通心络两种药物为H型高血压颈动脉粥样硬化患者实施治疗的具体效用。方法任意抽选本院2013年7月~2014年8月接收的66例H型高血压颈动脉粥样硬化患者，按照平均分组的方式将33例患者归类为对照组，另外33例患者则归类到观察组。单独使用阿托伐他汀为对照组实施药物治疗，观察组同时服用通心络以及阿托伐他汀两种药物进行治疗，比较患者血脂、血压指数以及HCY的控制效果。结果观察组的患者在血脂、血压指数以及HCY数值等方面的控制效果均比对照组更好，同时观察组患者在治疗期间发生不良反应的概率对照组更低（P＜0.05）。结论医院应普及同时运用通心络以及阿托伐他汀两种药物为H型高血压并发CAS患者实施救治的方案。
목적：연구동시운용아탁벌타정이급통심락량충약물위H형고혈압경동맥죽양경화환자실시치료적구체효용。방법임의추선본원2013년7월~2014년8월접수적66례H형고혈압경동맥죽양경화환자，안조평균분조적방식장33례환자귀류위대조조，령외33례환자칙귀류도관찰조。단독사용아탁벌타정위대조조실시약물치료，관찰조동시복용통심락이급아탁벌타정량충약물진행치료，비교환자혈지、혈압지수이급HCY적공제효과。결과관찰조적환자재혈지、혈압지수이급HCY수치등방면적공제효과균비대조조경호，동시관찰조환자재치료기간발생불량반응적개솔대조조경저（P＜0.05）。결론의원응보급동시운용통심락이급아탁벌타정량충약물위H형고혈압병발CAS환자실시구치적방안。
Objective To study the effectiveness of using two drugs-atorvastatin and Tongxinluo at the same time for the treatment of H type hypertension with carotid atherosclerosis with the implementation of speciifc therapeutic utility. Methods 66 cases of type H hypertension with carotid atherosclerosis were randomly selected, among them 33 patients were classiifed as control group, and the other 33 patients were classiifed as observation group. The control group received separate use of atorvastatin, while the observation group was treated both by Tongxinluo capsule and atorvastatin at the same time, the patients’ blood lipids , blood pressure index and Hcy control effect were compared. Results The control effect of blood lipid, blood pressure index and Hcy data in observation group were all better than in the control group (P<0.05). Conclusion Hospitals should popularize the application of combining atorvastatin and Tongxinluo in the treatment of H type hypertension with carotid atherosclerosis.