中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2015年
2期
10-11,12
,共3页
钙离子%脓毒症%APACHEⅡ
鈣離子%膿毒癥%APACHEⅡ
개리자%농독증%APACHEⅡ
Calcium%Sepsis%APACHEⅡ
目的：探讨脓毒症患者血清钙离子水平与疾病严重度及预后的相关性。方法：选取2008年1月-2013年12月在笔者所在医院ICU病房治疗的68例脓毒血症患者，根据脓毒症的严重程度分为轻度组20例、重度组30例和休克组18例，根据是否存活将其分为存活组51例与死亡组17例。另选正常体检者30例作为正常组。观察比较各组入ICU 24 h内的血清Ca2+水平及APACHEⅡ评分。结果：脓毒症患者的血清Ca2+水平均明显低于正常组，差异均有统计学意义(P<0.05)，且轻度组>重度组>休克组(P<0.05)。三组的APACHEⅡ评分比较，轻度组<重度组<休克组(P<0.05)，死亡组的血清Ca2+水平明显低于存活组，而APACHEⅡ评分明显高于存活组，差异均有统计学意义(P<0.05)。血清Ca2+水平与APACHEⅡ评分呈显著负相关性(r=0.618，P=0.00)。结论：血清Ca2+作为一种血清学指标，检查简便、快速，且与脓毒症患者APACHEⅡ评分有较强的相关性。可联合监测脓毒症患者APACHEⅡ评分及血清Ca2+对病情进行评估，制定合理诊疗方案，以改善患者的预后，提高存活率。
目的：探討膿毒癥患者血清鈣離子水平與疾病嚴重度及預後的相關性。方法：選取2008年1月-2013年12月在筆者所在醫院ICU病房治療的68例膿毒血癥患者，根據膿毒癥的嚴重程度分為輕度組20例、重度組30例和休剋組18例，根據是否存活將其分為存活組51例與死亡組17例。另選正常體檢者30例作為正常組。觀察比較各組入ICU 24 h內的血清Ca2+水平及APACHEⅡ評分。結果：膿毒癥患者的血清Ca2+水平均明顯低于正常組，差異均有統計學意義(P<0.05)，且輕度組>重度組>休剋組(P<0.05)。三組的APACHEⅡ評分比較，輕度組<重度組<休剋組(P<0.05)，死亡組的血清Ca2+水平明顯低于存活組，而APACHEⅡ評分明顯高于存活組，差異均有統計學意義(P<0.05)。血清Ca2+水平與APACHEⅡ評分呈顯著負相關性(r=0.618，P=0.00)。結論：血清Ca2+作為一種血清學指標，檢查簡便、快速，且與膿毒癥患者APACHEⅡ評分有較彊的相關性。可聯閤鑑測膿毒癥患者APACHEⅡ評分及血清Ca2+對病情進行評估，製定閤理診療方案，以改善患者的預後，提高存活率。
목적：탐토농독증환자혈청개리자수평여질병엄중도급예후적상관성。방법：선취2008년1월-2013년12월재필자소재의원ICU병방치료적68례농독혈증환자，근거농독증적엄중정도분위경도조20례、중도조30례화휴극조18례，근거시부존활장기분위존활조51례여사망조17례。령선정상체검자30례작위정상조。관찰비교각조입ICU 24 h내적혈청Ca2+수평급APACHEⅡ평분。결과：농독증환자적혈청Ca2+수평균명현저우정상조，차이균유통계학의의(P<0.05)，차경도조>중도조>휴극조(P<0.05)。삼조적APACHEⅡ평분비교，경도조<중도조<휴극조(P<0.05)，사망조적혈청Ca2+수평명현저우존활조，이APACHEⅡ평분명현고우존활조，차이균유통계학의의(P<0.05)。혈청Ca2+수평여APACHEⅡ평분정현저부상관성(r=0.618，P=0.00)。결론：혈청Ca2+작위일충혈청학지표，검사간편、쾌속，차여농독증환자APACHEⅡ평분유교강적상관성。가연합감측농독증환자APACHEⅡ평분급혈청Ca2+대병정진행평고，제정합리진료방안，이개선환자적예후，제고존활솔。
Objective:To investigate the correlation study between serum calcium ion level and disease severity and prognosis in sepsis patients. Method:68 sepsis patients in ICU ward of our hospital from January 2008 to December 2013 were selected,they were divided into the mild group for 20 cases, the severe group for 30 cases and the shock group for 18 cases according to sepsis severity.They were divided into the survival group for 51 cases and the death group for 17 cases according to whether survival.Another 30 healthy cases were selected as the control group.The serum Ca2+level and APACHEⅡscore within 24 h after admitted to ICU of each groups were observed and compared.Result:The serum Ca2+levels of patients with sepsis were significantly lower than that of normal group,the differences were statistically significant(P<0.05),and the serum Ca2+level of mild group was significantly higher than that of severe group,and that of severe group was significantly higher than that of shock group(P<0.05).Comparison of APACHEⅡscore in the three groups,that of the mild group was significantly less than the severe group,and that of the severe group was significantly less than the shock group(P<0.05).The serum Ca2+level of death group was significantly lower than that of survival group,the APACHEⅡscore of death group was significantly higher than that of survival group,the differences were statistically significant(P<0.05).There was a significant negative correlation between serum Ca2+level and APACHEⅡscore(r=0.618,P=0.00).Conclusion:The serum Ca2+as a serological index,the examination is simple,fast.There is a strong correlation between APACHEⅡscore and serum Ca2+of sepsis patients.The combined detection of APACHEⅡscore and serum Ca2+of sepsis patients can assess the disease and formulate reasonable treatment plan,in order to improve the prognosis of patients,improve the survival rate.
