CAJ | 학술논문

目的：探讨磁共振扩散加权成像对肝癌TACE治疗后肿瘤存活情况的判断价值。方法：选取笔者所在医院经TACE治疗的35例肝癌患者作为研究对象，术后8周均行增强磁共振和DWI扫描。残存的肿瘤评估采用欧洲肝脏研究协会制定的标准，回顾性分析肿瘤治疗后坏死组织和残存肿瘤的ADC值。结果：坏死组织的平均ADC值为(2.03±0.27)×10-3 mm2/s，残存肿瘤组织平均ADC值为(1.55±0.28)×10-3 mm2/s，两两比较差异有统计学意义(P<0.05)。ROC曲线分析显示：ADC阈值为(1.91±0.18)×10-3 mm2/s时，判断坏死组织的敏感性、特异性为89.2%和91.6%。结论：磁共振扩散加权成像可有效评估肝癌TACE治疗后的肿瘤坏死与肿瘤残存，为临床下一步治疗提供依据。
목적：탐토자공진확산가권성상대간암TACE치료후종류존활정황적판단개치。방법：선취필자소재의원경TACE치료적35례간암환자작위연구대상，술후8주균행증강자공진화DWI소묘。잔존적종류평고채용구주간장연구협회제정적표준，회고성분석종류치료후배사조직화잔존종류적ADC치。결과：배사조직적평균ADC치위(2.03±0.27)×10-3 mm2/s，잔존종류조직평균ADC치위(1.55±0.28)×10-3 mm2/s，량량비교차이유통계학의의(P<0.05)。ROC곡선분석현시：ADC역치위(1.91±0.18)×10-3 mm2/s시，판단배사조직적민감성、특이성위89.2%화91.6%。결론：자공진확산가권성상가유효평고간암TACE치료후적종류배사여종류잔존，위림상하일보치료제공의거。
Objective:To investigate the judgment value of diffusion-weighted imaging on the tumor survival of hepatocellular carcinoma after transcatheter arterial chemoembolization treatment.Method:A total of 35 patients with transcatheter arterial chemoembolization treatment according to chemoembolization protocols in our hospital were selected as research objects.After 8 weeks,they underwent enhanced magnetic resonance imaging and DWI scan on the same day. The presence of any residual tumor and the extent of tumor necrosis were evaluated according to the European Association for the Study of the Liver.The apparent diffusion coefficient (ADC) values of the vital and necrotic tumor tissues were recorded.Result:The mean ADC values of the necrotic and vital tumor tissues were (2.03±0.27)×10-3 mm2/s and (1.55±0.28)×10-3 mm2/s,the difference was statistically significant(P<0.05).The results from the receiver operating characteristic analysis showed that the threshold ADC value was (1.91±0.18)×10-3 mm2/s with 89.2%sensitivity and 91.6%specificity for identifying the necrotic tumor tissues. Conclusion:Diffusion-weighted imaging can be used to assess the tumor necrosis and residual tumor of hepatocellular carcinoma after TACE treatment,provide the basis data for clinical treatment.