CAJ | 학술논문

炎症是具有血管系统的活体组织对各种损伤因子的刺激所发生的防御反应，在人体许多重大疾病的发生发展过程中起着极其重要的作用。临床上应用的抗炎药物主要有非甾体类抗炎药、甾体类抗炎药和中草药。由于现有的化学合成抗炎药物具有明显的不良反应，近年来人们越来越重视从天然产物中寻找、开发抗炎药物。以往的综述主要侧重于天然药物的抗炎机制，而对于天然药物中抗炎活性成分的总结却少有报道，笔者对近年来报道的具有抗炎作用的天然药物活性成分的研究进行综述，以期对进一步开发高效安全的抗炎药物提供参考。
염증시구유혈관계통적활체조직대각충손상인자적자격소발생적방어반응，재인체허다중대질병적발생발전과정중기착겁기중요적작용。림상상응용적항염약물주요유비치체류항염약、치체류항염약화중초약。유우현유적화학합성항염약물구유명현적불량반응，근년래인문월래월중시종천연산물중심조、개발항염약물。이왕적종술주요측중우천연약물적항염궤제，이대우천연약물중항염활성성분적총결각소유보도，필자대근년래보도적구유항염작용적천연약물활성성분적연구진행종술，이기대진일보개발고효안전적항염약물제공삼고。
Inflammation is the defense response of the living tissues possessing vascular system to stimulations of various injury factors ,which plays a vital role in the initiation and progression of many major diseases .Drugs used to treat inflammation in the clinical mainly include non‐steroidal anti‐inflammatory drugs (NSAIDs) ,steroidal anti‐inflammatory drugs (SAIDs) and traditional Chinese medicine .As synthetic anti‐inflammatory drugs used in clinical currently have obvious adverse reactions , more and more attention were paid to seek anti‐inflammatory drugs from natural medicines .Reviews reported before mainly fo‐cus on anti‐inflammation mechanism of natural medicine ,however ,there are few reports on the summary of anti‐inflammatory natural products .Active natural products which were reported to possess anti‐inflammatory effects in recent years were summa‐rized in order to provide information for further study of anti‐inflammatory drugs research .