药学实践杂志
藥學實踐雜誌
약학실천잡지
THE JOURNAL OF PHARMACEUTICAL PRACTICE
2015年
1期
80-82
,共3页
肝硬化%失代偿期%药物经济学%成本-效果分析%保肝方案
肝硬化%失代償期%藥物經濟學%成本-效果分析%保肝方案
간경화%실대상기%약물경제학%성본-효과분석%보간방안
cirrhosis%decompensated period%drug economics%cost-effectiveness analysis%protect liver scheme
目的：运用药物经济学原理和方法对两种保肝治疗方案进行成本‐效果分析，为肝硬化失代偿期的患者选择较优的治疗方案提供依据。方法选择2010－2012年入院，诊断为肝硬化失代偿期，符合Chlid‐Pugh分级为B～C级的患者。将入选患者分为A、B、C3组，分别应用复方二氯醋酸二异丙胺注射液、多烯磷脂酰胆碱注射液、复方二氯醋酸二异丙胺注射液联合多烯磷脂酰胆碱注射液进行保肝治疗，但由于A组的Child‐Pugh分级所占比例与B组、C组存在统计学差异，排除A组，只观察B、C两组的疗效，并进行成本‐效果分析。结果 B、C两组的治疗时间分别为（15．5±8．55）d和（12．13±7．61）d；总有效率分别为50％和60％，差异无统计学意义（ P＞0．05）。而两组的总成本分别为（1640．52±905．26）元和（2576．51±1615．99）元，有显著性差异。结论 B组方案较佳。
目的：運用藥物經濟學原理和方法對兩種保肝治療方案進行成本‐效果分析，為肝硬化失代償期的患者選擇較優的治療方案提供依據。方法選擇2010－2012年入院，診斷為肝硬化失代償期，符閤Chlid‐Pugh分級為B～C級的患者。將入選患者分為A、B、C3組，分彆應用複方二氯醋痠二異丙胺註射液、多烯燐脂酰膽堿註射液、複方二氯醋痠二異丙胺註射液聯閤多烯燐脂酰膽堿註射液進行保肝治療，但由于A組的Child‐Pugh分級所佔比例與B組、C組存在統計學差異，排除A組，隻觀察B、C兩組的療效，併進行成本‐效果分析。結果 B、C兩組的治療時間分彆為（15．5±8．55）d和（12．13±7．61）d；總有效率分彆為50％和60％，差異無統計學意義（ P＞0．05）。而兩組的總成本分彆為（1640．52±905．26）元和（2576．51±1615．99）元，有顯著性差異。結論 B組方案較佳。
목적：운용약물경제학원리화방법대량충보간치료방안진행성본‐효과분석，위간경화실대상기적환자선택교우적치료방안제공의거。방법선택2010－2012년입원，진단위간경화실대상기，부합Chlid‐Pugh분급위B～C급적환자。장입선환자분위A、B、C3조，분별응용복방이록작산이이병알주사액、다희린지선담감주사액、복방이록작산이이병알주사액연합다희린지선담감주사액진행보간치료，단유우A조적Child‐Pugh분급소점비례여B조、C조존재통계학차이，배제A조，지관찰B、C량조적료효，병진행성본‐효과분석。결과 B、C량조적치료시간분별위（15．5±8．55）d화（12．13±7．61）d；총유효솔분별위50％화60％，차이무통계학의의（ P＞0．05）。이량조적총성본분별위（1640．52±905．26）원화（2576．51±1615．99）원，유현저성차이。결론 B조방안교가。
Objective To evaluate two treatment schemes of liver protection and choose the optimal radiotherapy using phar‐macoeconomics principle and methods .Methods In‐patients who were diagnosed as decompensated cirrhosis patients and simultaneously conformed to the Chlid‐Pugh graduation of level B‐C during 2010-2012 were chosen .The chosen patients were divided into A ,B and C group separately ,and were treated with the compound prescription of dichloro acetic acid two isopropyl amine inoculation fluid ,the poly‐ene phosphatide acid radical choline inoculation fluid ,and the compound prescription dichloro acetic acid two isopropyl amine inoculation fluid and the polyene phosphatide acid radical choline inoculation fluid .Cost effectiveness analysis was done between group B and C .Re‐sults Treatment time of group B and C was (15 .5 ± 8 .55) d and (12 .13 ± 7 .61) d respectively .The total effectiveness was 50% and 60% respectively and the difference was with non‐statistics significance (P>0 .05) .The total cost was (1 640 .52 ± 905 .26) yuan and (2 576 .51 ± 1 615 .99) yuan respectively .Conclusion Group B was the better treatment scheme .
