中国康复理论与实践
中國康複理論與實踐
중국강복이론여실천
CHINESE JOURNAL OF REHABILITATION THEORY & PRACTICE
2015年
1期
69-73
,共5页
张华%王昊%李多多%贾宝林%谭中建%陈红
張華%王昊%李多多%賈寶林%譚中建%陳紅
장화%왕호%리다다%가보림%담중건%진홍
颈椎病%慢性疼痛%默认网络%支持向量机%独立成分分析
頸椎病%慢性疼痛%默認網絡%支持嚮量機%獨立成分分析
경추병%만성동통%묵인망락%지지향량궤%독립성분분석
cervical spondylosis%chronic pain%default mode network%support vector machine%independent component analysis
目的:研究颈椎病慢性疼痛患者静息态默认网络的变化。方法健康人8名,患者10例行功能磁共振成像检查。采用独立成分分析分离基于皮层的默认网络,采用基于支持向量机分类方法找出区别正常组和患者组的成分脑区。结果慢性疼痛患者默认网络多个脑区连接强度均与对照组有差异。结论颈椎病慢性疼痛患者的默认网络连接强度与正常人不同,可能与疼痛患者的感知觉加工、情绪和记忆功能变化相关。
目的:研究頸椎病慢性疼痛患者靜息態默認網絡的變化。方法健康人8名,患者10例行功能磁共振成像檢查。採用獨立成分分析分離基于皮層的默認網絡,採用基于支持嚮量機分類方法找齣區彆正常組和患者組的成分腦區。結果慢性疼痛患者默認網絡多箇腦區連接彊度均與對照組有差異。結論頸椎病慢性疼痛患者的默認網絡連接彊度與正常人不同,可能與疼痛患者的感知覺加工、情緒和記憶功能變化相關。
목적:연구경추병만성동통환자정식태묵인망락적변화。방법건강인8명,환자10례행공능자공진성상검사。채용독립성분분석분리기우피층적묵인망락,채용기우지지향량궤분류방법조출구별정상조화환자조적성분뇌구。결과만성동통환자묵인망락다개뇌구련접강도균여대조조유차이。결론경추병만성동통환자적묵인망락련접강도여정상인불동,가능여동통환자적감지각가공、정서화기억공능변화상관。
Objective To explore the changes of resting state default mode network (DMN) in patients with chronic pain caused by cer-vical spondylosis (CPCS). Methods 8 healthy controls and 10 patients accepted functional MRI scanning. Surface based DMN was extract-ed with independent component analysis (ICA). The functional connectivity of the components of DMN were discriminated with support vector machine (SVM) algorithm from the patients to the controls. Results The DMN connectivity was different in the patients from the con-trols in some of the component areas. Conclusion DMN of CPCS patients is disorder in multiple brain areas, which may be involved with dysfunction of perception processing, emotion and memory.