中国康复理论与实践
中國康複理論與實踐
중국강복이론여실천
CHINESE JOURNAL OF REHABILITATION THEORY & PRACTICE
2015年
1期
62-64
,共3页
视黄醇结合蛋白4%糖尿病%血管病变%冠状动脉性心脏病%动脉粥样硬化%综述
視黃醇結閤蛋白4%糖尿病%血管病變%冠狀動脈性心髒病%動脈粥樣硬化%綜述
시황순결합단백4%당뇨병%혈관병변%관상동맥성심장병%동맥죽양경화%종술
retinol binding protein 4%diabetes mellitus%vascular disease%coronary heart disease%atheroselerosis%review
视黄醇结合蛋白4(RBP4)是一种由肝脏合成、存在于血液循环中的脂肪细胞因子。它与糖尿病大血管并发症的发生密切相关,同时也可能促进了糖尿病微血管病变的发生和发展。本文概述RBP4的结构和功能,及其与冠心病、动脉粥样硬化、糖尿病肾病、糖尿病视网膜病变关系的研究进展。
視黃醇結閤蛋白4(RBP4)是一種由肝髒閤成、存在于血液循環中的脂肪細胞因子。它與糖尿病大血管併髮癥的髮生密切相關,同時也可能促進瞭糖尿病微血管病變的髮生和髮展。本文概述RBP4的結構和功能,及其與冠心病、動脈粥樣硬化、糖尿病腎病、糖尿病視網膜病變關繫的研究進展。
시황순결합단백4(RBP4)시일충유간장합성、존재우혈액순배중적지방세포인자。타여당뇨병대혈관병발증적발생밀절상관,동시야가능촉진료당뇨병미혈관병변적발생화발전。본문개술RBP4적결구화공능,급기여관심병、동맥죽양경화、당뇨병신병、당뇨병시망막병변관계적연구진전。
Retinol binding protein 4 (RBP4), synthesized in the liver, is an adipocytokine existing in the circulation. It is closely related to the incidence of macrovascular complications of diabetes. It also promotes the occurrence and development of diabetic microangiopathy. This paper summarized the progress in the field about the structure and function of RBP4, RBP4 and coronary heart disease and atheroscle-rosis, as well as RBP4 and diabetic nephropathy and diabetic retinopathy.