中西医结合心血管病电子杂志
中西醫結閤心血管病電子雜誌
중서의결합심혈관병전자잡지
Cardiovascular Disease Journal of Integrated Traditional Chinese and Western Medicine (Electronic)
2014年
11期
140-142
,共3页
尹黎波%刘永霞%周滟%曾亚苹%魏敏%雷容霞
尹黎波%劉永霞%週滟%曾亞蘋%魏敏%雷容霞
윤려파%류영하%주염%증아평%위민%뢰용하
重症%心力衰竭%中心静脉压%B型脑钠肽%容量复苏
重癥%心力衰竭%中心靜脈壓%B型腦鈉肽%容量複囌
중증%심력쇠갈%중심정맥압%B형뇌납태%용량복소
Intensive%Heart failure%Central venous pressure%B-type brain natriuretic peptide%Capacity recovery
目的:探讨联合监测脑钠肽(BNP)、中心静脉压(CVP)在急性心衰早期治疗中的临床意义。方法选取50例入住ICU的危重心衰患者,随机分为:对照组(CVP组)25例和试验组(CVP+BNP组)25例;采用床旁干化学免疫法快速测定患者血浆BNP,有创心电监护测量CVP。试验组补液方法按照监测CVP及BNP来指导。对照组按CVP进行补液抗心衰治疗。评价治疗后72 h内两组患者BNP水平及心功能改善情况。结果治疗组与试验组患者BNP6 h、24 h、48 h、72 h水平分别为(412±131)ng/ml、(764±254)ng/ml、(432±213)ng/ml、(369±175)ng/ml;(631±172)ng/ml、(960±106)ng/ml、(857±121)ng/ml、(707.1±223.4)ng/ml,经比较,治疗组与试验组BNP6 h、24 h、48 h、72 h水平差异有统计学意义(P<0.05)。治疗组与试验组患者LVEF6 h、24 h、48 h、72 h水平差异有统计学意义(P<0.05)。治疗组与试验组患者治疗前心功能分级差异无统计学意义(P>0.05),治疗后心功能分级差异有统计学意义(P<0.05)。结论 CVP与BNP在重症疾患合并急性心衰中均增高,联合监测BNP、CVP可以提高患者疗效,降低BNP、CVP水平,更好指导容量管理。
目的:探討聯閤鑑測腦鈉肽(BNP)、中心靜脈壓(CVP)在急性心衰早期治療中的臨床意義。方法選取50例入住ICU的危重心衰患者,隨機分為:對照組(CVP組)25例和試驗組(CVP+BNP組)25例;採用床徬榦化學免疫法快速測定患者血漿BNP,有創心電鑑護測量CVP。試驗組補液方法按照鑑測CVP及BNP來指導。對照組按CVP進行補液抗心衰治療。評價治療後72 h內兩組患者BNP水平及心功能改善情況。結果治療組與試驗組患者BNP6 h、24 h、48 h、72 h水平分彆為(412±131)ng/ml、(764±254)ng/ml、(432±213)ng/ml、(369±175)ng/ml;(631±172)ng/ml、(960±106)ng/ml、(857±121)ng/ml、(707.1±223.4)ng/ml,經比較,治療組與試驗組BNP6 h、24 h、48 h、72 h水平差異有統計學意義(P<0.05)。治療組與試驗組患者LVEF6 h、24 h、48 h、72 h水平差異有統計學意義(P<0.05)。治療組與試驗組患者治療前心功能分級差異無統計學意義(P>0.05),治療後心功能分級差異有統計學意義(P<0.05)。結論 CVP與BNP在重癥疾患閤併急性心衰中均增高,聯閤鑑測BNP、CVP可以提高患者療效,降低BNP、CVP水平,更好指導容量管理。
목적:탐토연합감측뇌납태(BNP)、중심정맥압(CVP)재급성심쇠조기치료중적림상의의。방법선취50례입주ICU적위중심쇠환자,수궤분위:대조조(CVP조)25례화시험조(CVP+BNP조)25례;채용상방간화학면역법쾌속측정환자혈장BNP,유창심전감호측량CVP。시험조보액방법안조감측CVP급BNP래지도。대조조안CVP진행보액항심쇠치료。평개치료후72 h내량조환자BNP수평급심공능개선정황。결과치료조여시험조환자BNP6 h、24 h、48 h、72 h수평분별위(412±131)ng/ml、(764±254)ng/ml、(432±213)ng/ml、(369±175)ng/ml;(631±172)ng/ml、(960±106)ng/ml、(857±121)ng/ml、(707.1±223.4)ng/ml,경비교,치료조여시험조BNP6 h、24 h、48 h、72 h수평차이유통계학의의(P<0.05)。치료조여시험조환자LVEF6 h、24 h、48 h、72 h수평차이유통계학의의(P<0.05)。치료조여시험조환자치료전심공능분급차이무통계학의의(P>0.05),치료후심공능분급차이유통계학의의(P<0.05)。결론 CVP여BNP재중증질환합병급성심쇠중균증고,연합감측BNP、CVP가이제고환자료효,강저BNP、CVP수평,경호지도용량관리。
Objective To evaluate The Clinical value of CVP and BNP in earlyh heart failure. Methods Selected 50 cases of ICU heart failure patients, and randomly divided into: the control group (CVP) 25 cases and experimental group+BNP (CVP) 25 cases; The bed dry chemical immunoassay (ELISA) in patients with rapid determination of plasma BNP, invasive measuring CVP ecg monitoring. According to the monitoring of CVP to guide group rehydration method. The control group rehydration anti-shock treatment according to CVP. Evaluation within 72 h after treatment of two groups of patients with BNP levels.Results Treatment group and experimental group patients BNP6h, 24 h, 48 h, 72 h, respectively (412±131; 764±254; 432±213; 369±175; 631±172; 960±106; 857±121; 707.1±223.4),by comparison, the treatment group and experimental group BNP6h, 24 h, 48 h, 72 h level difference was statistically signiifcant(P<0.05).Treatment group and experimental group patients LVEF6h, 24 h, 48 h, 72 h level difference was statistically signiifcant(P<0.05). Treatment group and experimental group before treatment in patients with cardiac function classification has no statistically significant difference (P>0.05), the treatment of middle of the back function grade difference was statistically signiifcant (P<0.05).Conclusion The CVP and BNP are higher in the severe disease complicating acute heart failure, reasonable monitoring the BNP, CVP can improve patient treatment effect, reduce the level of BNP, CVP.